Healthcare News | Medical Research

Innate Immunity Has a Role in Vitiligo Pathogenesis

Innate immunity may play a role in susceptibility to vitiligo, a new study showed.

Rasha Turky Abdel-Razek Abdel-Aziz, of Minia University, Minia, Egypt, and colleagues recently published the results of a cross-sectional comparative study that showed a significant difference in the distribution of the Toll-like receptor (TLR)9 rs187084 between patients with vitiligo and those without.

COVID-19’s Impact on Biopsy Rates, IgAN Diagnoses Within the European Union

Katie KoskoIgA Nephropathy | May 20, 2025

A study found low rates of IgAN in the EU, but lower biopsy rates during the COVID-19 pandemic may have delayed diagnoses.

Successful HIV Viral Suppression With At-Home Administration

Jordana JampelHIV | May 20, 2025

At-home administration was safe, effective, and had higher participant satisfaction.

New Data on Terlipressin Presented at DDW 2025

Peter Richardson, BMedSci, BM, BS, MRCPAcute Kidney Injury | May 20, 2025

Drs. Peter Richardson and George Wan of Mallinckrodt Pharmaceuticals discussed new data on terlipressin for HRS-AKI.

Kidney Organizations Join Forces to Develop Framework for Glomerular Disease Centers of Excellence

Charlotte RobinsonIgA Nephropathy | May 20, 2025

Three kidney organizations will develop a consensus framework for Centers of Excellence in Glomerular Disease Care.

Targeted-Release Budesonide Shows Benefit for Patients With Severe Renal Impairment

Katie KoskoIgA Nephropathy | May 19, 2025

Nefecon can safely be used to treat severe renal impairment and lowers proteinuria in patients with IgAN.

Phase 2 Data Support a Safer Immunotherapy Option for PNH

Andrew MorenoPNH | May 19, 2025

A novel complement-targeting agent shows impressive efficacy and safety without immunosuppression of the classical pathway.

Modernization and the Rising Burden of IBD: New Insights From a Global Study

Jordana JampelGastroenterology | May 19, 2025

The developed scale strengthens the investigation of global irritable bowel disease epidemiology.

ASN to Launch Centers of Excellence in Home Dialysis Pilot Program

Charlotte RobinsonEnd-Stage Renal Disease | May 19, 2025

The American Society of Nephrology (ASN) will create a Centers of Excellence in Home Dialysis pilot program.

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The Latest From GI Oncology Now

Suvemcitug Combination Shows Promise in MSS/pMMR Colorectal Cancer

Emily MenendezColorectal Cancer | March 17, 2025

Suvemcitug, envafolimab, and FOLFIRI may serve as a new second-line treatment option for cold tumors.

Genetic Resistance to KRASG12C Inhibitors in CRC and PDAC

Emily MenendezPancreatic Cancer | March 17, 2025

KRASG12C inhibitors can have reduced efficacy in patients with alterations in KRAS, EGFR, and other genes.

Complete Response to Immunotherapy in HCC: Insights From IMbrave150

Emily MenendezLiver Cancer | March 14, 2025

Complete responders with HCC have prolonged survival and durable disease control even after therapy has been discontinued.

177Lu-edotreotide Improves PFS, OS Over Everolimus for SSTR-Positive GEP-NETs

Emily MenendezGEP-NETs | March 12, 2025

The primary objective of median PFS was significantly longer for patients treated with 177Lu-edotreotide.

MATTERHORN: Durvalumab Plus FLOT Improves EFS and pCR in Gastric, GEJ Cancers

Emily MenendezGastroesophageal Cancer | March 12, 2025

The safety profile of the combination was consistent with known profiles, and no new safety findings were observed.

Risk for Choledocholithiasis Higher in Older Adult Patients With Cholangiocarcinoma

Emily MenendezBile Duct Cancer | March 11, 2025

Older patients in their 70s with extrahepatic CCA have a higher rate of choledocholithiasis.

The Latest From Heme Today

Phase 2 Data Support a Safer Immunotherapy Option for PNH

Andrew MorenoPNH | May 19, 2025

A novel complement-targeting agent shows impressive efficacy and safety without immunosuppression of the classical pathway.

Is Plasma Mannose-Binding Lectin a Clue to Higher VTE Risk?

Andrew MorenoVTE | May 16, 2025

Investigation of a HUNT Study cohort found elevated plasma MBL levels to be associated with increased risk for future VTE.

Study Data Bolster Quercetin Treatment of Fanconi Anemia in Young Persons

Andrew MorenoAnemia | May 16, 2025

Reactive oxygen species levels decreased and patients with evident bone marrow failure showed hematological response.

Extending Anticoagulation is Reasonable in Children with VTE, Data Suggest

Andrew MorenoVTE | May 19, 2025

A cohort study of extended-phase anticoagulation following acute management was performed in the phase III EINSTEIN Jr trial.

Hemophilia B Gene Therapy Shows Promise as Long-Term Treatment

Melissa BadamoHemophilia | May 13, 2025

Fidanacogene elaparvovec gene therapy is a safe and effective treatment for patients with hemophilia B, research shows.

Oral Histone Deacetylase Inhibitor Receives FDA Fast Track Designation for PV

Andrew MorenoPolycythemia Vera | May 12, 2025

The agent targets abnormal gene expression in order to control the excessive cell proliferation that occurs in PV.

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