IgAN
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FILSPARI (sparsentan) has received conditional marketing authorization from the European Commission to treat IgAN in adults.
Interim analysis from the APPLAUSE-IgAN trial found favorable results for the use of iptacopan in IgAN.
Longer follow-up results of the RUBY-3 trial found povetacicept is well-tolerated and shows promise for IgAN treatment.
Researchers found that sparsentan had a clinically meaningful benefit on long-term kidney preservation versus irbesartan.
Vertex Pharmaceuticals will acquire Alpine Immune Sciences, developer of povetacicept for IgA nephropathy.
Results from a trial of atacicept for the treatment of IgAN will be presented at the European Renal Association Congress.
Results of the RUBY-3 study of povetacicept for IgAN will be presented at the ISN World Congress of Nephrology.
APRIL has emerged as a critical factor in the pathogenesis of IgAN and is the focus of several clinical development programs.
Worldwide, immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis.
Clinical manifestations associated with IgAN include hematuria, proteinuria, and hypertension.
Where patients reported nausea/vomiting, it was not recognized by nephrologists in 85% of cases.
Worldwide, immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis.
A study sought to discern surrogate endpoints that could serve as robust predictors of treatment efficacy on long-term ...
A study shows that sustained proteinuria is a strong predictor for the rate of progression of renal disease, and ...
Worldwide, immunoglobulin A nephropathy (IgAN) is the most common primary glomerular disease and a major cause of kidney ...
In a recent clinical trial, researchers led by Gaiqin Pei, MM, sought to examine the effect of immunosuppression ...
Immunoglobulin A nephrology (IgAN) is the most common biopsy-proven glomerular disease. Patients who develop IgAN ...
The most common primary glomerulonephritis is immunoglobin A (IgA) nephropathy (IgAN), a leading cause of kidney ...
Renal pathology is critical in clinical management and prognosis in patients with immunoglobulin A nephropathy (IgAN)
Worldwide, the most prevalent form of primary glomerular disease is immunoglobulin A nephropathy. Progresses from ...
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