ECLIPSE on Orbital Atherectomy: Balloon Angioplasty Still Shines in Calcified Lesions

The ECLIPSE trial, presented at TCT 2024, investigated whether orbital atherectomy (OA) provides better outcomes than conventional balloon angioplasty in patients with severely calcified coronary lesions undergoing percutaneous coronary intervention (PCI). Despite initial expectations that atherectomy could improve lesion modification and stent expansion in calcified vessels, the trial found no significant advantage of OA over balloon angioplasty for most clinical outcomes.

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