Markers of pulmonary impairment and inflammation were elevated in children with sickle cell disease and acute chest syndrome. A FDA Advisory Committee endorsed the safety of exa-cel, a genetic therapy with the potential to cure sickle cell disease. Oral deferiprone yielded outcomes comparable to subcutaneous deferoxamine for pediatric patients with sickle cell disease. Take a look at these important studies relevant to anemia, venous thromboembolism, sickle cell disease, and PNH. Research showed the historical effect of pneumococcal conjugate vaccines on infections in children with sickle cell disease. Stem cell gene therapy showed potential as a curative approach for the hereditary blood disorder sickle cell disease. Pediatric patients with SCD undergoing orthopedic surgery are at an increased risk of perioperative complications. In pediatric patients with sick cell disease, red blood cell transfusion increases alloimmunization. A study investigated potential variations in pain trajectories based on sex and other factors in adolescents with SCD. Psychosocial variables are more strongly associated with pain impact in individuals with SCD than biological variables. Sickle cell trait is associated with adverse pregnancy outcomes in non-Hispanic Black women. V114, a 15-valent pneumococcal vaccine, was safe and effective in children with sickle cell disease in a phase 3 trial. Pulmonary embolism is challenging to diagnose due to its nonspecific symptoms, including abdominal pain. Some demographic and preexisting medical conditions are associated with adverse outcomes in COVID-19, including chronic ... For patients with sickle cell disease (SCD), the Wells’ Criteria for Pulmonary Embolism demonstrated acceptable ... Compared with other etiologies of kidney failure, patients who initiate dialysis due to kidney failure associated with ... Various indications for sickle cell disease call for red blood cell exchange.. Last month, a trial of a gene therapy for sickle cell disease (SCD) from Bluebird Bio, Inc. was halted after two study ... When physicians suspect a diagnosis of certain conditions, a referral to a hematologist is warranted. Sickle cell disease (SCD) shortens life expectancy and leads to morbidity. Recent advancements in allogeneic ...