Breast Cancer

Neoadjuvant Immunity: Oncolytic Virus + Chemo Shows Promise in Early TNBC

Hatem Soliman, MDTriple-Negative Breast Cancer | June 12, 2025

TVEC plus chemo shows promise in early TNBC, boosting immune response and survival with favorable safety profile.

How AI Is Reshaping Oncology Practice: Insights From ASCO’s AI Task Force

Debra Patt, MD, PhD, MBABreast Cancer News | June 12, 2025

Dr. Patt discusses how AI is transforming oncology care, and how to implement it responsibly and effectively.

ReDiscover Trial: Novel PI3Kα Inhibitor RLY-2608 Shows Promising Safety, Efficacy

Sarah Sammons, MDHR Breast Cancer | June 12, 2025

Dr. Sammons on RLY-2608 plus fulvestrant in HR+/HER2– mBC with PIK3CA mutations: safety, efficacy, and trial updates.

HER2+ Practice-Changing Data From ASCO 2025 With Dr. Rebecca Shatsky

Rebecca Shatsky, MDHER2 Breast Cancer | June 10, 2025

Dr. Shatsky weighs DESTINY-Breast09 findings and highlights the need to balance efficacy with long-term quality of life.

Emi-Le ADC Targets B7-H4 in TNBC and Beyond: Promising Early Efficacy with Novel Payload

Erika P. Hamilton, MDTriple-Negative Breast Cancer | June 9, 2025

Emi-Le ADC shows promising activity in B7-H4–positive TNBC and endometrial cancer with a novel auristatin payload.

Shifting First-Line Strategy: Inavolisib Shows OS, PFS Gains in INAVO120 Trial

Sibylle Loibl, MDHR Breast Cancer | June 9, 2025

INAVO120 shows OS benefit with inavolisib in PIK3CA-mutated HR+/HER2– aBC, raising new considerations for first-line care.

Can We Improve Second-Line Outcomes in ESR1-Mutated mBC? Insights From ADELA

Antonio Llombart Cussac, MD, PhDHR Breast Cancer | June 11, 2025

ADELA trial explores elacestrant + everolimus for ESR1-mutated breast cancer post-CDK4/6, aiming to boost 2L outcomes.

Dr. Rebecca Shatsky on the Top Breakthroughs in TNBC at ASCO 2025

Rebecca Shatsky, MDTriple-Negative Breast Cancer | June 9, 2025

New ASCENT-04 data could shift first-line care in PD-L1+ TNBC. Dr. Rebecca Shatsky shares real-world insights from ASCO 2025.

Treating Brain and Leptomeningeal Metastases: Promising TUXEDO-3 Data with HER3-Directed ADC

Rupert Bartsch, MDHER2 Breast Cancer | June 6, 2025

HER3-DXd shows promise for CNS metastases in breast and lung cancer in the TUXEDO-3 trial, including patients with LMD.

Interpreting ASCENT-04 Findings With Dr. Sarah Tolaney

Sara Tolaney, MD, MPHTriple-Negative Breast Cancer | June 6, 2025

Sacituzumab + pembrolizumab improved PFS vs chemo in PD-L1+ TNBC in ASCENT-04, with no new safety signals.

Expert Interviews on Oncology

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Section Editor

Dr. Sadie Dobrozsi, EvolentHematologist/oncologist and Medical Director, Evolent