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ESMO 2024: GI Oncology Now

The European Society for Medical Oncology Congress 2024 took place in Barcelona, Spain on September 13-16.

Follow along as we share pre-meeting viewpoints, onsite coverage, and post-meeting recaps, complete with expert interviews, article summaries, and more related to gastrointestinal malignancies.

Latest News

mFOLFIRINOX Plus Preop Chemoradiation Therapy: No Primary Endpoint Improvements

Jordana JampelPancreatic Cancer | September 19, 2024

mFOLFIRINOX plus CRT did not improve R0 resection nor OS compared with nFOLFIRINOX without CRT.

Preoperative CRT Versus Perioperative CT for Gastric Cancer: The TOPGEAR Study

Trevor Leong, MDGastric Cancer | September 18, 2024

Dr. Leong showcases the highly anticipated results of the TOPGEAR study in patients with resectable G/GEJ adenocarcinoma.

Second-line nal-IRI: No PFS Improvement With S-1, Promising OS With 5-FU

Jordana JampelPancreatic Cancer | September 17, 2024

The primary endpoint was PFS, which was a median of 3.5 months for S-1 and 3.7 months for 5-FU.

Moonlight: New Data Points for FOLFOX, Nivo/Ipi, FLOT in EGA

Jordana JampelGastroesophageal Cancer | September 17, 2024

FLOT and nivo seems to be associated with improved efficacy, whereas chemo followed by IO therapy is insufficient.

LEAP-012: Lenvatinib Plus Pembrolizumab Improves PFS in Intermediate-Stage HCC

Brandon TwyfordGI Cancer | September 18, 2024

The LEAP-012 study showed improved progression-free survival with lenvatinib, pembrolizumab, and TACE in HCC.

Does Adding Preoperative CRT to Perioperative Chemotherapy Improve Survival for Resectable Gastric Cancer?

Zachary BessetteGastric Cancer | September 17, 2024

The addition of preop CRT to periop chemo may not have added OS benefit for patients with resectable G/GEJ adenocarcinoma.

ESMO24 GI Review: LEAP-012, TOPGEAR, and EMERALD

Zev Wainberg, MD, MScGastric Cancer | September 17, 2024

Dr. Wainberg reviews the data on GI malignancies and notes that it is unclear who should receive radiation before surgery.

LEAP-012: PFS Benefit With Pembrolizumab, Levatinib, and TACE vs TACE Alone

Josep M. Llovet, MDGI Cancer | September 17, 2024

Dr. Josep Llovet discusses promising data, including higher PFS and OS, in metastatic liver cancer from the LEAP-012 trial.

DESTINY-Gastric03: Analyzing Trastuzumab Deruxtecan for Gastric and GEJ Cancers

Yelena Janjigian, MDGastric Cancer | September 16, 2024

Dr. Janjigian shares an overview of the DESTINY-Gastric03 study and the history of T-Dxd for gastric and GEJ cancers.

BREAKWATER Trial: Encorafenib Plus Cetuximab With FOLFIRI Shows Strong Efficacy in BRAF V600E-mutant mCRC

Brandon TwyfordColorectal Cancer | September 16, 2024

Combining encorafenib and cetuximab with FOLFIRI chemotherapy showed strong antitumor activity in BRAF V600E-mutant mCRC.

Roundtable Discussions

Oncology Brothers Event Coverage

Advancements in Oncology: GI Cancer

GI Oncology Now has exclusive coverage of Advancement in Oncology: Today’s Data for Tomorrow’s Practice, the first event co-hosted by The Oncology Brothers and Mashup Media. Review the breakthrough data on gastrointestinal cancers presented at the event and insights from esteemed experts that bridge the gap between research and practice for community oncologists.

Conference Coverage

ESMO 2024: GI Oncology Now

The latest news and research updates in GI cancer treatment from the ESMO Congress 2024

ASCO 2024: GI Oncology Now

The latest news and research updates in GI cancer treatment from the ASCO 2024 Annual Meeting

ASCO GI Symposium 2024

GI Oncology Now reviews education from ASCO GI 2024, featuring the latest advances in the field of GI cancer research.

International Society of Gastrointestinal Oncology 2023 Annual Meeting

GI Oncology Now reviews education from ISGIO 2023, featuring the latest advances in the field of GI cancer research.

Expert Interviews

Benjamin Weinberg, MD, FACPEditor | Associate Professor of Medicine at Lombardi Comprehensive Cancer Center

Zev Wainberg, MD, MScEditor | Co-Director of Gastrointestinal Oncology at the University of California, Los Angeles