Gastroesophageal Cancer
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Dr. Ronan Kelly describes his trial on nivolumab with relatlimab for the treatment of resectable esophageal/GEJ cancer.
The prognostic value of the Edmonton Symptom Assessment Scale in patients with gastroesophageal cancer was investigated.
For those with a PD-L1 CPS of 5 or higher who received the combination therapy, the median OS was not achieved.
Chromoendoscopic screening can help reduce esophageal cancer incidence and mortality rates.
The trial’s primary endpoint was safety and the secondary endpoint was feasibility.
Tislelizumab correlated with a higher objective response rate and a better durable antitumor response versus chemotherapy.
Research has shown that trifluridine-tipiracil may increase survival benefit for patients with metastatic EGA.
Dr. Janjigian discusses how the agent - created with invariant natural killer t-cells - works in tandem with other therapies.
Dr. Janjigian describes the history behind nivolumab treatment, and the differences in initial results versus follow-up.
Patients received 2 cycles of sintilimab, paclitaxel, and carboplatin once every 21 days.
Results of the PANDA study show that atezo has an additive effect with chemo in eliciting tumor response in early G/GEJ.
The study investigated if avelumab and paclitaxel plus ramucirumab would constitute an effective second-line treatment.
The ESCORT-NEO study explored the use of neoadjuvant camrelizumab with chemotherapy followed by adjuvant camrelizumab.
Twice-weekly docetaxel plus 5-FU has previously exhibited encouraging antitumor activity.
Manish A. Shah, MD, and colleagues are reporting 5-year follow-up data from the randomized, phase 3 KEYNOTE-590 study.
The benefits of combination neoadjuvant and adjuvant chemotherapy and immune checkpoint inhibition are currently unknown.
Esophageal cancer is the sixth leading cause of cancer-related deaths and the eighth most common form of cancer worldwide.
Findings from the EDGE-Gastric trial suggest potential for 2 novel agents in patients with gastroesophageal adenocarcinoma.
The anastomotic leakage rate in the SGC group appeared significantly lower than in the NGC cohort.
An analysis found that esophageal cancer rates have declined in the United States since 2004.
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