Dr. Vadivelan shared her study on pituitary and pancreatic iron deposition in patients with SCD at the 2024 ASPHO Conference. Dr. Ansong-Ansongton shared what National Minority Health Month and Celebrate Diversity Month mean to him at ASPHO 2024. Dr. Ansong-Ansongton described data on the impact of abnormal mitochondrial retention and cold in red blood cells in SCD. Dr. Mamauag details her study on the need for factor VIII infusions in patients with tolerized hemophilia A on emicizumab. Dr. Sharathkumar shared data from her 2024 ASPHO presentation on romiplostim in children with severe aplastic anemia and MDS. The study evaluated transplant outcomes in pediatric patients with SCD who had a history of red blood cell alloimmunization. Dr. Griffin shares data from their real-world study on pegcetacoplan in patients with paroxysmal nocturnal hemoglobinuria. Dr. Grunwald of the Atrium Health Levine Cancer Institute, discusses caring for patients with PV on rare disease day. Dr. Pakbaz describes some of the difficulties faced by patients with SCD as they switch from pediatric to adult programs. Drs. Grant, Sutin, and Lin discuss their pilot study investigating cerebral hemodynamics in infants with sickle cell disease. Dr. Pakbaz and Dr. Strouse discuss their experiences practicing classical hematology and where the speciality is heading. Dr. Pakbaz, from the University of California Irvine, shared data on the value of a dedicated classical hematology clinic. Dr. Pakbaz describes the significant need for specialists dedicated to adult patients with noncancer blood disorders. Dr. Hobbs shared findings supporting the safety and feasibility of continuing ruxolitinib during and after HSCT for MF. The panel shares their outlook for the future of MDS research and treatment. Dr. Tanaka outlines a biomarker study that observed reduced inflammation in patients with MDS treated with luspatercept. The panel discussed a study that assessed quality of life and PROs in patients receiving luspatercept for MDS. The panel discusses whether starting treatment with luspatercept sooner in patients with MDS is beneficial. Dr. Shammo shares her reaction to a study that assessed mutational burden and impact on primary outcomes in COMMANDS. Dr. Safah outlines the findings from the full analysis of the COMMANDS trial.