Kaitlyn D’Onofrio

DocwireNews

A recent study published in&nbsp;The New England Journal of Medicine&nbsp;found five target areas for people with type 2 diabetes&nbsp;in order to&nbsp;decrease their chance of death,&nbsp;myocardial infarction, or stroke:&nbsp;elevated glycated hemoglobin level, elevated low-density lipoprotein cholesterol level, albuminuria, smoking, and elevated blood pressure.&nbsp;The cohort study included 271,174 type 2 diabetes patients and 1,355,870 age-, sex-, and county-matched controls.&nbsp;Researchers followed up after a mean of 5.7 years. For diabetic patients whose risk factors were in the target ranges, when compared with the controls, the hazard ratios (HR) were 1.06 for death by any cause, 0.84 for acute myocardial infection, and 0.95 for stroke. HR for hospitalization for heart failure among the diabetic group was 1.45. For the type 2 diabetes patients, smoking was the strongest predictor of death, and an elevated glycated hemoglobin level was the greatest predictor of stroke and acute myocardial infarction.&nbsp;<blockquote class="twitter-tweet" data-width="500" data-dnt="true">
Original Article: Risk Factors, Mortality, and Cardiovascular Outcomes in Patients with Type 2 Diabetes <a href="https://t.co/gURQcykvvg">https://t.co/gURQcykvvg</a> <a href="https://t.co/sJx4tOAtqE">pic.twitter.com/sJx4tOAtqE</a>
&mdash; NEJM (@NEJM) <a href="https://twitter.com/NEJM/status/1034776510547329030?ref_src=twsrc%5Etfw">August 29, 2018</a>
</blockquote><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>&ldquo;The study indicates that having all five risk-factor variables within the target ranges could theoretically eliminate the excess risk of acute myocardial infarction,&rdquo;&nbsp;the study authors wrote.&nbsp;What makes the study unique compared to previous clinical trials is that it focuses on targeting multiple risk factors at once,&nbsp;lead author&nbsp;Dr.&nbsp;Aidin&nbsp;Rawshani&nbsp;told TCTMD.&nbsp;&ldquo;There are only a few clinical trials that have studied the importance of treating several risk factors at once, compared to usual care for these risk factors,&rdquo; he said.&nbsp;<blockquote class="twitter-tweet" data-width="500" data-dnt="true">
<a href="https://twitter.com/hashtag/Diabetes?src=hash&amp;ref_src=twsrc%5Etfw">#Diabetes</a> doesn&rsquo;t always show obvious symptoms, so it&rsquo;s good to know the risk factors. Find out if you&rsquo;re at risk: <a href="https://t.co/IW5gw92PRp">https://t.co/IW5gw92PRp</a> <a href="https://t.co/WdgMlrzyHw">pic.twitter.com/WdgMlrzyHw</a>
&mdash; CDC Diabetes (@CDCDiabetes) <a href="https://twitter.com/CDCDiabetes/status/1033524310151856128?ref_src=twsrc%5Etfw">August 26, 2018</a>
</blockquote><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>In an accompanying&nbsp;<a href="https://www.nejm.org/doi/full/10.1056/NEJMe1809004">editorial</a>, Dr. Steven&nbsp;Schroeder&nbsp;noted that targeting risk factors may be more difficult for members of certain vulnerable populations.&nbsp;&ldquo;A cautionary note is that pathways to target levels of risk factor variables are not always straightforward and often involve issues of lifestyle, adherence to medication, and other behaviors that are hard to modify, despite best attempts,&rdquo;&nbsp;Schroeder&nbsp;wrote. &ldquo;For vulnerable populations, risk factor control may be especially challenging, as shown by the widening health gap between social classes.&rdquo;&nbsp;<blockquote class="twitter-tweet" data-width="500" data-dnt="true">
Many people are unaware of the risk factors and symptoms of type 2 diabetes. Learn more about your risk and what action you can take to reduce it.<a href="https://t.co/9NtblgZsRH">https://t.co/9NtblgZsRH</a> <a href="https://t.co/0nheqLs3gS">pic.twitter.com/0nheqLs3gS</a>
&mdash; Int. Diabetes Fed. (@IntDiabetesFed) <a href="https://twitter.com/IntDiabetesFed/status/1032649503881478145?ref_src=twsrc%5Etfw">August 23, 2018</a>
</blockquote><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>Sources:&nbsp;<a href="https://www.nejm.org/doi/full/10.1056/NEJMoa1800256">New England Journal of Medicine</a>, <a href="https://www.tctmd.com/news/type-2-diabetes-five-risk-factor-targets-keep-mi-stroke-and-death-check">TCTMD</a>&nbsp;

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Researchers Assess Five Risk Factors to Reduce Mortality in Type 2 Diabetes Patients

Diabetes

A recent study published in The New England Journal of Medicine found five target areas for people with type 2 diabetes in order to decrease their chance of ...

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