Tirzepatide linked to reduced muscle fat infiltration and volume in type 2 diabetes, per SURPASS-3 MRI substudy findings. Real-world weight loss with semaglutide or tirzepatide is lower due to early discontinuation and low maintenance dosing. Chronic hyperglycemia in pediatric type 1 diabetes may impair white matter development; brain changes persist into puberty. Nearly half of U.S. patients discontinued semaglutide within 5 months, with cost a key barrier to continued use. How many medications are FDA-approved for the long-term use of treating obesity? Habits collapsed, health's calling 'Mayday'! The doc soars in ... time to dose the FDA way! Obesity care must be evidence-based and patient-centered, says Dr. Auriemma in this call for science-driven treatment. Obesity is a chronic, complex disease driven by biology, not just behavior—effective care requires empathy and support. There was also an association with higher educational levels and odds of poor sleep quality. Higher HbA1c levels were a higher risk factor in children with lower BMIs. A new study investigated the effects of physical training on aging in the skeletal muscle of people with obesity. Researchers report a sharp increase in extreme forms of obesity in the U.S. Trachtenberg's sudden death highlights the dangers of diabetes, including chronic and transplant-related complications. The systematic review considered 144 studies that involved diabetes or obesity. The guideline supports "value- and preference-sensitive decision-making" for children with obesity and their families. A study shows geographic disparities that exist as they pertain to heart failure mortality and its association with obesity. PEGS were developed from whole-blood DNA methylation samples for items such as blood pressure, BMI, and C-reactive protein. GLP1 RA provides a notably superior weight loss option for people with obesity compared with bariatric surgery. A novel study shows a rising trend in cardiac tachyarrhythmia deaths related to obesity. A new study finds a striking increase in obesity prevalence among Black children during the COVID-19 pandemic.