Rajiv Agarwal discussed a study showing that a finerenone-empagliflozin combo has superior efficacy in CKD and T2D. Treatment with a finerenone-empagliflozin combo leads to greater decreases in albuminuria in CKD and type 2 diabetes. A study assessed whether the cardiovascular and renal effects of canagliflozin are dose dependent. Finerenone had kidney and cardiovascular benefits for patients with CKD even after an acute eGFR change occurred. A dual SGLT inhibitor may have ischemic benefits for patients with CKD, T2D, and cardiovascular risks, a study found. A study examined the effects of SGLT2i on eGFR slope in patients with autosomal dominant polycystic kidney disease. Researchers presented results of an interim analysis of a study of finerenone among patients with CKD and type 2 diabetes. A study examined the association of ankle-brachial index and CKD progression with type 2 diabetes and elevated BMI. Is metformin use ever appropriate for patients with advanced kidney disease and type 2 diabetes? Research examined kidney endpoints between patients with type 2 diabetes after initiating an SGLT2i or GLP-1RA. A review and meta-analysis assessed the influence of SGLT2i therapy on clinically relevant hyperuricemic events. Monlunabant failed in a study of its use in DKD, but Novo Nordisk had positive news about other kidney treatments in 2024. The FDA has approved Ozempic (semaglutide) to treat chronic kidney disease (CKD) in adults with type 2 diabetes. What is the association of gout with CV disease and mortality risk in patients with type 2 diabetes and can CKD modify it? Effects of SGLT2 inhibitors on renal outcomes in patients with CKD, heart failure, and type 2 diabetes were examined. Direct comparisons of kidney and cardiovascular outcomes with GLP-1 RAs and SGLT2i in type 2 diabetes are lacking. Semaglutide reduced the risk of death among patients in the FLOW trial, who had CKD and type 2 diabetes. FLOW trial data showed semaglutide safely reduced risks of major kidney outcomes regardless of CKD severity. What is the relationship between blood urea nitrogen-to-serum albumin ratio and mortality in ICU patients with T2D and CKD? The four-pillar approach to treating diabetic kidney disease (DKD) has been endorsed by high-quality trials, such as FLOW.