Rob Dillard

DocwireNews

<p>A new study reveals that the prognosis of <a href="https://www.docwirenews.com/docwire-pick/hem-onc-picks/early-and-repeated-exposure-to-diagnostic-imaging-increases-testicular-cancer-risk/">testicular cancer</a> has notably improved. The findings were <a href="https://ascopubs.org/doi/10.1200/JCO.20.03292">published</a> in the <em>Journal of Clinical Oncology.</em><p>While the classification of the International Germ-Cell Cancer Collaborative Group (IGCCCG) has provided major advancements in the management of germ-cell tumors, the classifications rely on data from only 660 patients with testicular cancer treated between 1975 and 1990. Therefore, the investigators re-evaluated this classification in a database from a large international consortium of patients.</p><div class="NLM_sec NLM_sec_level_1">
<p>In this new study, researchers collated data on 2,451 men with metastatic seminoma who treated with cisplatin- and etoposide-based first-line chemotherapy between 1990 and 2013. Clinical trial and registry data were included. The primary endpoints were defined as progression-free survival (PFS) and overall survival (OS), which were calculated from day 1 of treatment.</p>
<p>https://twitter.com/thedextazlab/status/1405561930157264902</p>
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<p>Compared with the initial IGCCCG classification, the researchers showed that in the modern series, 5-year PFS improved from 82% to 89% (95% CI, 87-90) while the 5-year OS increased from 86% to 95% (95% CI, 94-96) in good prognosis, and from 67% to 79% (95% CI, 70-85) and 72% to 88% (95% CI, 80-93) in intermediate prognosis patients. The next step, <a href="https://eurekalert.org/pub_releases/2021-06/ibuh-tci061721.php">according to</a> the investigators, will be to incorporate the findings&nbsp; into treatment guidelines and reduce the burden of cancer therapy.</p>
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<p lang="en" dir="ltr">Testicular <a href="https://twitter.com/hashtag/Cancer?src=hash&amp;ref_src=twsrc%5Etfw">#Cancer</a>: Improved treatment and prognosis <a href="https://t.co/vShba8ansE">https://t.co/vShba8ansE</a><a href="https://twitter.com/hashtag/science?src=hash&amp;ref_src=twsrc%5Etfw">#science</a> <a href="https://twitter.com/hashtag/MedicineHealth?src=hash&amp;ref_src=twsrc%5Etfw">#MedicineHealth</a> <a href="https://twitter.com/hashtag/ResearchDevelopment?src=hash&amp;ref_src=twsrc%5Etfw">#ResearchDevelopment</a> <a href="https://t.co/yQTuP7uoL9">pic.twitter.com/yQTuP7uoL9</a></p>
<p>&mdash; Bioengineer.org (@bioengineerorg) <a href="https://twitter.com/bioengineerorg/status/1405569509453447173?ref_src=twsrc%5Etfw">June 17, 2021</a></p>
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<p lang="en" dir="ltr">Improved treatment and better prognosis for testicular cancer patients</p>
<p>More medical news at <a href="https://t.co/DUWSlWzJcW">https://t.co/DUWSlWzJcW</a><a href="https://twitter.com/hashtag/Oncology?src=hash&amp;ref_src=twsrc%5Etfw">#Oncology</a> <a href="https://twitter.com/hashtag/MedTwitter?src=hash&amp;ref_src=twsrc%5Etfw">#MedTwitter</a> <a href="https://twitter.com/hashtag/MedEd?src=hash&amp;ref_src=twsrc%5Etfw">#MedEd</a><a href="https://t.co/wGg1bCZqgE">https://t.co/wGg1bCZqgE</a></p>
<p>&mdash; MedPub Oncology (@MedPubOnco) <a href="https://twitter.com/MedPubOnco/status/1405686560620752896?ref_src=twsrc%5Etfw">June 18, 2021</a></p>
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A new study reveals that the prognosis of testicular cancer has notably improved. The findings were published in the Journal of Clinical Oncology. ...

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