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Initiating stroke treatment just 15 minutes earlier could save additional lives and prevent disability, according to new research.The retrospective cohort <a href="https://jamanetwork.com/journals/jama/fullarticle/2738288?guestAccessKey=2e2523db-1471-47bf-819d-519754c4b845&amp;utm_source=For_The_Media&amp;utm_medium=referral&amp;utm_campaign=ftm_links&amp;utm_content=tfl&amp;utm_term=071619">study</a> out of UCLA and published in JAMA, looked at 6,756 patients with acute ischemic stroke. The used the <a href="https://www.docwirenews.com/cardiology/hospice-discharge-gwtg-hf/">Get With The Guidelines</a>-Stroke nationwide clinical registry to find patients with anterior circulation large vessel occlusion acute ischemic stroke treated with endovascular-reperfusion therapy with an onset-to-puncture time of eight hours or less. The primary endpoint of interest was substantial reperfusion (using modified Thrombolysis in Cerebral Infarction score of 2b-3), ambulatory status, global disability and destination at discharge, symptomatic intracranial hemorrhage, and in-hospital mortality/discharge. Mean patient age was 69.5 years (51.2% women).Median onset-to-puncture time was was 230 minutes, with a door-to-puncture time of 87 minutes; 85.9% of patients had substantial reperfusion. Within the 30- to 270-minute time frame, increments of 15 minutes in onset-to-puncture time were linked with a higher likelihood of achieving independent ambulation at hospital discharge (absolute increase, 1.14%). The researchers also reported lower in-hospital mortality/hospital discharge (absolute decrease, -0.77%) and a lower risk for intracranial hemorrhage (absolute decrease, -0.22%). In addition, faster door-to-puncture times were associated with an increased likelihood of home discharge (increase of 2.13%) and lower rates of in-hospital mortality/hospice discharge (absolute decrease, -1.48%).&ldquo;Among patients with acute ischemic stroke due to large vessel occlusion treated in routine clinical practice, shorter time to endovascular-reperfusion therapy was significantly associated with better outcomes,&rdquo; thee researchers wrote in their conclusion. &ldquo;These findings support efforts to reduce time to hospital and endovascular treatment in patients with stroke.&rdquo;<blockquote class="twitter-tweet" data-width="500" data-dnt="true">
Every minute counts in acute ischemic stroke care. Latest findings from GWTG-Stroke. Endovascular Reperfusion Therapy and Acute Ischemic Stroke Outcomes <a href="https://t.co/qAsfovViQM">https://t.co/qAsfovViQM</a>. <a href="https://twitter.com/AHA_Research?ref_src=twsrc%5Etfw">@AHA_Research</a> <a href="https://twitter.com/American_Stroke?ref_src=twsrc%5Etfw">@American_Stroke</a> <a href="https://twitter.com/Braindoc_MGH?ref_src=twsrc%5Etfw">@Braindoc_MGH</a> <a href="https://twitter.com/AHAScience?ref_src=twsrc%5Etfw">@AHAScience</a> <a href="https://twitter.com/NancyatHeart?ref_src=twsrc%5Etfw">@NancyatHeart</a> <a href="https://twitter.com/JAMANetwork?ref_src=twsrc%5Etfw">@JAMANetwork</a> <a href="https://twitter.com/JAMAForum?ref_src=twsrc%5Etfw">@JAMAForum</a>
&mdash; Gregg Fonarow MD (@gcfmd) <a href="https://twitter.com/gcfmd/status/1151245161046790144?ref_src=twsrc%5Etfw">July 16, 2019</a>
</blockquote><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script><blockquote class="twitter-tweet" data-width="500" data-dnt="true">
<a href="https://twitter.com/hashtag/TimeIsBrain?src=hash&amp;ref_src=twsrc%5Etfw">#TimeIsBrain</a> &ndash; faster onset-reperfusion times associated with ambulation and functional independence! Endovascular Reperfusion Therapy and Acute Ischemic Stroke Outcomes <a href="https://t.co/oKVat8fC9W">https://t.co/oKVat8fC9W</a>
&mdash; Justin Singer MD, FAANS (@JustinSingerMD) <a href="https://twitter.com/JustinSingerMD/status/1151289262379286529?ref_src=twsrc%5Etfw">July 17, 2019</a>
</blockquote><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>https://twitter.com/mward04/status/1151495415772172289

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Improving Intervention Time for Stroke by 15 Minutes Saves Lives: Study

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Initiating stroke treatment just 15 minutes earlier could save additional lives and prevent disability, according to new research. ...

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