Rob Dillard

DocwireNews

Blood clot rates in <a href="https://www.docwirenews.com/docwire-pick/hem-onc-picks/covid-19-update-first-americans-could-receive-vaccine-by-early-next-month-astrazeneca-vaccine-is-70-effective-and-more/">COVID-19</a> patients are high, and associated with an increased risk of death, according to a study published in The Lancet.To conduct this study, researchers performed a systematic review and meta-analysis of studies evaluating thromboembolism (TE) in COVID-19. After We combing PubMed, Cochrane, and Embase for studies published up to June 12, 2020, they identified 425 studies &ndash; of which 42 were included in analysis. The total number of studies comprised 8,271 patients.According to the results, the verall venous TE rate was 21% (95% CI,17 to 26%), while the ICU rate was 31% (95% CI, 23 to 39%). Overall deep vein thrombosis rate was 20% (95% CI, 13 to 28%). Overall, the study showed that the mortality rates were 74% higher among patients with COVID-19 who developed TE juxtaposed to those who did not (OR=1.74; 95%CI, 1.01&ndash;2.98; P&nbsp;=&nbsp;0.04).&ldquo;We began to notice a really unusual manifestation of venous and arterial thromboembolism in patients with COVID-19,&rdquo; said lead researcher Mahmoud Malas, MD, division chief of Vascular and Endovascular Surgery at UC San Diego Health <a href="https://www.eurekalert.org/pub_releases/2020-11/uoc--sci112320.php">via a</a> press release. &ldquo;In addition to higher instances of blood clots, the mortality for patients hospitalized for COVID-19 and with thromboembolism was much higher, compared to patients without clots. It&rsquo;s unusual because we have never seen anything like this with other respiratory infections.&rdquo;&ldquo;The collective experience in the literature as captured in this meta-analysis study brings additional light on the importance of blood vessel clotting events in hospitalized patients with COVID-19,&rdquo; said Bryan Clary, MD, surgeon-in-chief at UC San Diego Health and co-author of the study. &ldquo;While the frequency of these events is much higher than expected, our study likely underestimates the incidence of thromboembolism in the global population of patients with COVID-19, including non-hospitalized patients.&rdquo;<blockquote class="twitter-tweet" data-width="500" data-dnt="true">
SDBN Feed: Study: COVID-19 Infection Combined with Blood Clots Worsen Patient Outcomes &ndash; <a href="https://t.co/VdyuCxdqBR">https://t.co/VdyuCxdqBR</a> <a href="https://twitter.com/hashtag/biotech?src=hash&amp;ref_src=twsrc%5Etfw">#biotech</a> <a href="https://twitter.com/hashtag/news?src=hash&amp;ref_src=twsrc%5Etfw">#news</a> <a href="https://t.co/Fw4YzaiEVz">pic.twitter.com/Fw4YzaiEVz</a>
&mdash; San Diego Biotech Networks (@sdbn) <a href="https://twitter.com/sdbn/status/1330941373390987265?ref_src=twsrc%5Etfw">November 23, 2020</a>
</blockquote><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>&nbsp;&ldquo;What we can learn from this paper is due diligence,&rdquo; added Dr. Malas. &ldquo;We&rsquo;re still in the process of understanding the pathophysiology of COVID-19, so it&rsquo;s important to have a low index of suspicion when it comes to this infection to ensure we&rsquo;re doing all we can to mitigate the spread and prevent severe outcomes.&rdquo;

Jeffrey Perl, MD

Joel M. Topf, MD, FACP

Thoughts From the 2025 Lazarus Award Winner

NKF Spring Clinical Meetings 2025

Brandon Twyford

DESTINY-Breast09 Demonstrates First-Line Superiority of Enhertu Plus Pertuzumab in HER2-Positive Metastatic Breast Cancer

HER2 Breast Cancer

Trodelvy Plus Keytruda Significantly Improves Progression-Free Survival in PD-L1+ mTNBC, Phase III Data Show

Triple-Negative Breast Cancer

Latest News

COVID-19 Associated with Increased Blood Clots, and Clotting Increases the Risk of Death in COVID Patients

Blood clot rates in COVID-19 patients are high, and associated with an increased risk of death, according to a study published in The Lancet.
 ...

COVID-19 Associated with Increased Blood Clots, and Clotting Increases the Risk of Death in COVID

About Us

Editorial Policy

Advertising

Contact Us

eNewsletters

Contribute

Career Center

MashupMD

Blood Cancers Today

Cancer Nursing Today

GU Oncology Now

Urban Health Today

Bile Duct Cancer

Colorectal Cancer

Gastroesophageal Cancer

Gastric Cancer

GEP-NETs

GIST

Liver Cancer

Pancreatic Cancer

GI Oncology Now

Anemia

Deep Vein Thrombosis

Essential Thrombocythemia

Hemophilia

Immune Thrombocytopenic Purpura

Myelodysplastic Syndromes

Myelofibrosis

Myeloproliferative Neoplasms

Polycythemia Vera

Pulmonary Embolism

Sickle Cell Disease

Thrombocytopenia

Thrombophilia

Thrombosis

Thrombotic Thrombocytopenic Purpura

Venous Thromboembolism

von Willebrand Disease

Heme Today

Acute Kidney Injury

ADPKD

Anemia and Kidney Disease

Chronic Kidney Disease

COVID-19 and Kidney Disease

Diabetes and Hypertension

End-Stage Renal Disease

Gout

Hyperkalemia

IgAN

Kidney Transplantation

Metabolic Acidosis

Nephrology Times

HR Breast Cancer

Genetics & Breast Cancer

Breast Cancers Today

Atherosclerotic Disease

Atrial Fibrillation

Heart Failure

Hypertension

Interventional Cardiology

Lipid Management

Practice Tips With Dr. Lichaa

Preventive Cardiology

Stroke

Cardiology

Breast Cancer

Gynecologic Cancer

Head and Neck Cancer

Skin Cancer

Oncology

Sleep

Urology

Diabetes

Ophthalmology

— Demodex Blepharitis

Neurology

Rheumatology

Gastroenterology

Pulmonology

Infectious Diseases

— HIV

Health and Wellness

Lupus

Future of Medicine

Orthopedics

Pharmacology

Career News

More

Conferences

CardioNerds

The Sleep Source With Dr. Morse

Rheumatology Rounds With Dr. Maheswaranathan

Partners

Expert Interviews

Subscribe