Kidney Transplantation
Part of NephTimes
34 Lives received a $44 million grant to support No Kidney Left Behind, a project to extend the viability of donated kidneys. A proposed HHS rule would remove barriers and increase access to kidney and liver transplantation in the HIV community. Felzartamab was found to be a safe and effective treatment for antibody-mediated rejection in kidney transplantation. eGenesis has received financing to help advance an engineered kidney, EGEN-2784, to a first-in-human study for transplant. Makana Therapeutics has discovered a fourth pig gene that, when inactivated, could greatly reduce organ rejection risk. CMS will rescind a proposed draft coverage policy that would have limited coverage of noninvasive post-transplant monitoring. The End Kidney Deaths Act would provide tax credits to living donors who give kidneys to patients waitlisted the longest. A new pretransplant risk assessment assay may help determine risk of early acute kidney transplant rejection. Older kidney donors are now more common, but the safety of nephrectomy in donors aged ≥70 years has not been well studied. In March, a patient at the Cleveland Clinic became the first in the US to receive a robot-assisted dual kidney transplant. Are kidneys from donors who had dialysis more likely to result in adverse outcomes for transplant recipients? OPTN will remove race and hepatitis C status from the KDPI, the formula that estimates donor kidney quality. A study examined whether donors have a higher risk of hypertension than nondonors in the first 7 years after kidney donation. Xiaoxi Wei of X-Therma spoke about her company's preservation platform and how it can change organ transplantation. Investigational cellular product MDR-101 produced immune tolerance in kidney transplant recipients. PASC symptoms were common in solid organ transplant recipients during the Omicron period, but some patients had lower odds. Consent for donor kidneys with lower expected survival varies but consent results in a higher likelihood of transplantation. Researchers compared results from an AI model to predict kidney transplant rejection risk by histological diagnosis. Researchers examined whether eplet-based matching could lead to disparities in deceased donor kidney transplantation access. SARS-CoV2 T-cell responses are largely preserved despite T-cell depletion induction in kidney transplant.