Kerri Fitzgerald

DocwireNews

A study published in&nbsp;The Lancet Oncology&nbsp;found that&nbsp;maternal hormonal&nbsp;birth control&nbsp;use affects non-lymphoid leukemia development in children.&nbsp;&ldquo;Since almost no risk factors have been established for childhood leukemia, these findings suggest an important direction for future research&nbsp;into its causes and prevention,&rdquo; the authors wrote.&nbsp;The&nbsp;study followed a nationwide cohort of more than 1 million&nbsp;liveborn children between January 1, 1996, and December 31, 2014,&nbsp;who were&nbsp;listed in the Danish Medical Birth Registry. The researchers&nbsp;identified those diagnosed with&nbsp;leukemia&nbsp;in the Danish Cancer Registry&nbsp;and&nbsp;used data&nbsp;from the Danish National Prescription Registry&nbsp;to identify redeemed prescriptions for&nbsp;maternal hormonal contraceptives. Birth control use was categorized&nbsp;as: no use (never used contraception before birth), previous use (&gt;3 months before start of pregnancy), and recent use (&le;3 months before and during pregnancy).&nbsp;&nbsp;<a href="https://twitter.com/CarrascalAlvaro/status/1039476651376238592">https://twitter.com/CarrascalAlvaro/status/1039476651376238592</a>During the study period,&nbsp;606 children were diagnosed with&nbsp;leukemia, including&nbsp;lymphoid&nbsp;leukemia&nbsp;(n=465)&nbsp;and non-lymphoid&nbsp;leukemia (n=141).&nbsp;&nbsp;Children born to women with recent use of any hormonal contraception were at higher risk for any&nbsp;leukemia&nbsp;than children&nbsp;born to&nbsp;women&nbsp;who never used&nbsp;this&nbsp;contraception (hazard ratio [HR] = 1.46;&nbsp;95% CI, 1.09-1.96;&nbsp;P=0.011). There was no association between timing of&nbsp;birth control&nbsp;use and risk for lymphoid&nbsp;leukemia&nbsp;(previous use,&nbsp;HR=1.23; 95% CI, 0.97-1.57;&nbsp;P=0.089&nbsp;versus recent use, HR=1.27;&nbsp;95% CI, 0.90-1.80;&nbsp;P=0.167).&nbsp;&nbsp;<blockquote class="twitter-tweet" data-width="500" data-dnt="true">
Article on use of hormonal contraception &amp; leukemia in kids. I cringe in anticipation of media handling. tl;dr: "Hormonal contraception use&hellip;might have resulted in one additional case of leukaemia per about 50k exposed children, or 25 cases [over 9 yrs]." <a href="https://t.co/59yXTqRoK5">https://t.co/59yXTqRoK5</a>
&mdash; Brendan Hayes (@brendanmhayes) <a href="https://twitter.com/brendanmhayes/status/1039224476800634880?ref_src=twsrc%5Etfw">September 10, 2018</a>
</blockquote><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>The&nbsp;researchers&nbsp;concluded that hormonal contraception use close to or during pregnancy might have resulted in one additional case of&nbsp;leukemia&nbsp;per about 50,000 exposed children,&nbsp;or 25 cases during the 9-year&nbsp;period.&nbsp;<a href="https://proddocwire.wpengine.com/hematology-oncology/lack-of-microbial-infection-early-in-life-could-lead-to-childhood-leukemia/">Lack of&nbsp;microbial&nbsp;infection&nbsp;early in&nbsp;life&nbsp;could&nbsp;lead to&nbsp;childhood&nbsp;leukemia.</a>&nbsp;<a href="https://proddocwire.wpengine.com/docwire-pick/aml-predicted-prevented/">Can AML&nbsp;be&nbsp;predicted and&nbsp;prevented&nbsp;years in&nbsp;advance?</a>&nbsp;Source:&nbsp;<a href="https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(18)30479-0/fulltext?rss=yes">The Lancet Oncology</a>&nbsp;

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Link Between Maternal Hormonal Birth Control Use and Childhood Leukemia?

Oncology

A study published in The Lancet Oncology found that maternal hormonal birth control use affects non-lymphoid leukemia development in children. “Since almost no risk ...

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