Kaitlyn D’Onofrio

DocwireNews

Respiratory viral infections may put patients at risk for developing <a href="https://www.docwirenews.com/docwire-pick/rheumatology-picks/what-do-rheumatologists-and-patients-value-most-when-making-ra-treatment-decisions/">rheumatoid arthritis</a> (RA), according to a report previously published in <a href="https://arthritis-research.biomedcentral.com/articles/10.1186/s13075-019-1977-9">Arthritis Research &amp; Therapy</a>, suggesting concerns for patients who develop coronavirus.&ldquo;In our study, parainfluenza, coronavirus, and metapneumovirus were significantly associated with the number of incident RA. The patterns of virus seasonality, the severity or virulence of infections, and the parameters such as peak age of viral infections have differential effects on the associations between each respiratory virus and incident RA. The similarity of the three significant respiratory viruses in the study has not been elucidated by one of the factors described above. More complex interactions among these virus factors or other environmental factors may be involved,&rdquo; the researchers observed.The study authors queried the Korean National Health Insurance (KNHI) claims database for records spanning 2011 through 2015; data collection included patients&rsquo; diagnoses, procedures, prescriptions, type of institution or department, and individual beneficiary information. The Korea Centers for Disease Control and Prevention database was queried for weekly observation data on coronavirus, as well as seven other respiratory viral infections: influenza, parainfluenza, adenovirus, respiratory syncytial virus (RSV), rhinovirus, metapneumovirus, and bocavirus.Between January 2012 and December 2013, 24,117 patients received a new RA diagnosis; mean age at diagnosis was 54.7 years. About three-quarters of patients diagnosed (77.5%) were female. The majority of patients (95%) had a national health insurance. Most of the new diagnoses were made at clinics (44.6%), while 31.6% were made at tertiary hospitals and 23.8% at general hospitals.<h2>Coronavirus Increases Incident RA Risk</h2>An association was observed between ambient respiratory viral infections in the population and an increase in incident RA over time, with a peak at six to seven weeks following exposure. The three viruses most associated with an increase in <a href="https://www.docwirenews.com/docwire-pick/rheumatology-picks/significant-racial-and-socioeconomic-disparities-persist-in-musculoskeletal-care-across-the-country/">incident RA</a> were parainfluenza virus (4.8% for 1% respiratory viral infection increase; 95% confidence interval [CI], 1.6 to 8.1; P=0.003), coronavirus (9.2%; 95% CI, 3.9 to 14.8, P&lt;0.001), and metapneumovirus (44%; 95% CI, 2.0 to 103.4; P=0.038). Patients who were impacted the most were women (3.8%, 12.1%, and 67.4%, respectively; P&lt;0.05) and older patients (10.7%, 14.6%, and 118.2%, respectively; P&lt;0.05).&ldquo;In the present study, RA development exhibited a seasonal tendency, and ambient parainfluenza, coronavirus, and metapneumovirus infections were associated with an increased number of incident RA. These results support the etiological hypothesis that respiratory viral infections in the population may have the capacity to trigger RA,&rdquo; the study authors concluded.

MarkAlain Déry, DO

The Significant Danger Measles Pose for Unvaccinated Children

Infectious Disease

Andrew Moreno

Antithrombotic Care in Hemophilia: A Summary of Multi-Organizational Clinical Practice Guidance

Hemophilia

James Tumlin, MD

Joel M. Topf, MD, FACP

Proteinuria Remission With Sparsentan in FSGS

NKF Spring Clinical Meetings 2025

Latest News

Coronavirus May Be a Risk Factor for Rheumatoid Arthritis

COVID-19

Respiratory viral infections may put patients at risk for developing rheumatoid arthritis (RA), according to a report previously published in Arthritis Research &amp; Therapy, ...

About Us

Editorial Policy

Advertising

Contact Us

eNewsletters

Contribute

Career Center

MashupMD

Blood Cancers Today

Cancer Nursing Today

GU Oncology Now

Urban Health Today

Bile Duct Cancer

Colorectal Cancer

Gastroesophageal Cancer

Gastric Cancer

GEP-NETs

GIST

Liver Cancer

Pancreatic Cancer

GI Oncology Now

Anemia

Deep Vein Thrombosis

Essential Thrombocythemia

Immune Thrombocytopenic Purpura

Myelodysplastic Syndromes

Myelofibrosis

Myeloproliferative Neoplasms

Polycythemia Vera

Pulmonary Embolism

Sickle Cell Disease

Thrombocytopenia

Thrombophilia

Thrombosis

Thrombotic Thrombocytopenic Purpura

Venous Thromboembolism

von Willebrand Disease

Heme Today

Acute Kidney Injury

ADPKD

Anemia and Kidney Disease

Chronic Kidney Disease

COVID-19 and Kidney Disease

Diabetes and Hypertension

End-Stage Renal Disease

Gout

Hyperkalemia

IgAN

Kidney Transplantation

Metabolic Acidosis

Nephrology Times

HER2 Breast Cancer

HR Breast Cancer

Triple-Negative Breast Cancer

Genetics & Breast Cancer

Breast Cancers Today

Atherosclerotic Disease

Atrial Fibrillation

Heart Failure

Hypertension

Interventional Cardiology

Lipid Management

Practice Tips With Dr. Lichaa

Preventive Cardiology

Stroke

Cardiology

Breast Cancer

Gynecologic Cancer

Head and Neck Cancer

Skin Cancer

Oncology

Sleep

Urology

Diabetes

Ophthalmology

— Demodex Blepharitis

Neurology

Rheumatology

Gastroenterology

Pulmonology

Infectious Diseases

— HIV

Health and Wellness

Lupus

Future of Medicine

Orthopedics

Pharmacology

Career News

More

Conferences

CardioNerds

The Sleep Source With Dr. Morse

Rheumatology Rounds With Dr. Maheswaranathan

Partners

Expert Interviews

Subscribe