Cryo-electron microscopy shed light on the molecular structure of urate transporter 1 and mechanisms behind four gout drugs.

Nephrology Times
Nephrology Times delivers the latest news in kidney-related treatments and technologies with the goal of better informing care decisions and improving patient outcomes.
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Latest News
Phase 3 VISIONARY trial data showed sibeprenlimab helps achieve significant proteinuria reduction in IgAN.
Gene sequencing of a patient with gouty sacroiliitis and gouty nephropathy highlighted genetic factors leading to gout.
Treatment with a finerenone-empagliflozin combo leads to greater decreases in albuminuria in CKD and type 2 diabetes.
Pegcetacoplan reduced proteinuria and stabilized eGFR in adolescent patients with C3G or primary IC-MPGN.
An analysis confirmed the efficacy and safety of pegcetacoplan for patients with C3G/IC-MPGN and nephrotic range proteinuria.
Treatment effects of nefecon were consistent independent of baseline eGFR among patients with IgAN.
Infliximab therapy for Crohn’s disease is linked to a high risk for IgAN, a study found.
A study highlights the role of NPT2b in tubulointerstitial fibrosis and CKD progression.
Researchers identified three immune phenotypes of checkpoint inhibitor-induced acute interstitial nephritis.
A study assessed whether the cardiovascular and renal effects of canagliflozin are dose dependent.
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Expert Interviews
Conferences
Podcasts
This Freely Filtered episode discusses the KDIGO guideline draft for autosomal dominant polycystic kidney disease (ADPKD).
This Freely Filtered episode discusses REGENCY, examining the efficacy and safety of obinutuzumab in active lupus nephritis.
Listen to the discussion of Chapter 18 of Dr. Burton Rose's book, focused on metabolic alkalosis.
Freely Filtered returns with another episode for NephMadness, this time, covering the hemodialysis region.
Expert Columns
Ajay Singh talks dialytrauma—harmful effects of dialysis in patients with AKI moving from inpatient to outpatient care.
Sarah Tolson reviews how changes to reimbursement for phosphate binders have affected dialysis programs.
Ajay Singh discusses the state of rare kidney disease research.
Sarah Tolson highlights the concerns and challenges dialysis programs face under the 2025 ESRD PPS requirements.
Dr. Ajay Singh and others pay tribute to Dr. Barry Brenner, a leading nephrologist who passed away in August 2024.
Sarah Tolson shares what billing departments of dialysis programs need to know about the CMS final rule for the ESRD PPS.