Anemia and Kidney Disease
Part of NephTimes
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Researchers examined the roles of hyperuricemia and anemia in all-cause mortality with chronic kidney disease (CKD).
The ERA reviewed phase 3 trials to clarify the mechanism behind HIF-PHi and their role in managing CKD-related anemia.
The FDA approved Vafseo (vadadustat) to treat anemia due to chronic kidney disease (CKD) in adults on dialysis.
SGLT2 inhibitors have benefits for anemia risk but their effectiveness among patients with T2D and CKD stage 1-3 was unclear.
Patients with early chronic kidney disease (CKD) frequently develop anemia.
In multivariate logistic regression analysis, a higher UFR was associated with lower hemoglobin levels.
Dr. Richard Lafayette discusses the FDA approval of TARPEYO, which reduces the loss of kidney function in IgA nephropathy.
The primary efficacy end point of interest was the mean change in hemoglobin from baseline over weeks 12 to 16.
Patients with chronic kidney disease (CKD) commonly develop anemia.
Trials included in the analysis compared HIF-PHIs to placebo or to erythropoiesis-stimulating agents (ESA).
Patients receiving maintenance hemodialysis who develop anemia are commonly treated with erythropoiesis-stimulating agents.
Patients with end-stage kidney disease with anemia are commonly treated with recombinant human erythropoietin.
There are associations between anemia in ESKD and increased risk of morbidity and mortality.
Interpatient variation in mean hemoglobin levels were smaller in the intervention arm than in the standard of care arm.
The results suggested that treatment with HIF-PHIs increased the level of hemoglobin.
One of the most common complications of chronic kidney disease (CKD) is renal anemia.
Extended storage of red blood cells correlated with increased transplant longevity following kidney transplant.
There were no differences seen in adverse events and serious adverse events among trial participants.
There were no statistically significant differences between the two groups in eGFR and proteinuria slopes.
There was a strong association between lower eGFR and increased prevalence of anemia across all categories of hemoglobin.
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