DocWire News Editors

DocwireNews

According to a study published in The Journal of Orthopaedic Research, non-invasive collection of biomarkers could be a possible method of predicting a patient&rsquo;s risk of osteolysis. Researchers assessed biomarkers present in urine samples from 26 patients who had total hip replacements, 16 of whom having osteolysis after operation. Biomarkers were examined annually for 6 years before diagnosis, prior to operation, and at the first sampling point after operation.Of the 7 candidate biomarkers observed, free deoxypyridinoline was most strongly related to risk of osteolysis, with an area under the curve (AUC) in Receiver Operating Characteristic (ROC) analyses of 0.844 at 6 years prior to diagnosis. An &alpha;&#8208;crosslaps and interleukin&#8208;6 containing panel identified those who were at risk of osteolysis with an AUC &gt; 0.941 at all biomarker collections after operation, and an AUC of 1.0 before operation.These results display the potential use of noninvasive biomarkers in determining a patient&rsquo;s risk for osteolysis after arthroplasty. The simplicity of the urine sample makes the diagnosis a practical and inexpensive procedure that can identify risk of osteolysis before it is present on radiographic imaging.Source:&nbsp;<a href="https://onlinelibrary.wiley.com/doi/pdf/10.1002/jor.24044">Journal of Orthopaedic Research</a>

Kaitlyn Kosko

Pembrolizumab Plus Trastuzumab/Pertuzumab Shows Promise in HER2-Positive Breast Cancer

HER2 Breast Cancer

MarkAlain Déry, DO, MPH, FACOI

Autism Rates Reach New High in U.S. Children: Here’s What It Really Means

Neurodivergent

Jordana Jampel

Annual US Measles Cases Top 1,000, Worst Year Since Elimination

Infectious Disease

Latest News

Noninvasive Collection of Biomarkers Could Indicate Risk of Osteolysis

Future of Medicine

According to a study published in The Journal of Orthopaedic Research, non-invasive collection of biomarkers could be a possible method of predicting a patient’s risk of ...

About Us

Editorial Policy

Advertising

Contact Us

eNewsletters

Contribute

Career Center

MashupMD

Blood Cancers Today

Cancer Nursing Today

GU Oncology Now

Urban Health Today

Anemia

Deep Vein Thrombosis

Essential Thrombocythemia

Hemophilia

Immune Thrombocytopenic Purpura

Myelodysplastic Syndromes

Myelofibrosis

Myeloproliferative Neoplasms

Polycythemia Vera

Pulmonary Embolism

Sickle Cell Disease

Thrombocytopenia

Thrombophilia

Thrombosis

Thrombotic Thrombocytopenic Purpura

Venous Thromboembolism

von Willebrand Disease

Heme Today

Acute Kidney Injury

ADPKD

Anemia and Kidney Disease

Chronic Kidney Disease

COVID-19 and Kidney Disease

Diabetes and Hypertension

End-Stage Renal Disease

Gout

Hyperkalemia

IgAN

Kidney Transplantation

Metabolic Acidosis

Nephrology Times

HR Breast Cancer

Triple-Negative Breast Cancer

Genetics & Breast Cancer

Breast Cancers Today

Atherosclerotic Disease

Atrial Fibrillation

Heart Failure

Hypertension

Interventional Cardiology

Lipid Management

Practice Tips With Dr. Lichaa

Preventive Cardiology

Stroke

Cardiology

Breast Cancer

Gynecologic Cancer

Head and Neck Cancer

Skin Cancer

Oncology

Sleep

Urology

Diabetes

Ophthalmology

— Demodex Blepharitis

Neurology

Rheumatology

Gastroenterology

Pulmonology

Infectious Diseases

— HIV

Health and Wellness

Lupus

Orthopedics

Pharmacology

Career News

More

Conferences

CardioNerds

The Sleep Source With Dr. Morse

Rheumatology Rounds With Dr. Maheswaranathan

Partners

Expert Interviews

Subscribe