Rob Dillard

DocwireNews

Fecal microbiota transplant (FMT)&nbsp;is a relatively safe and viable treatment option for acute gut graft-versus-host disease (GVHD), according to a study presented at the 2021 TCT Meetings of ASTCT &amp; CIBMTR Digital Experience.&ldquo;Many studies looking into the pathogenesis of gut GVHD have confirmed the hypothesis that patients with less diverse fecal microbiome have a greater chance of developing intestinal GVHD and are more prone to succumb to transplant-related complications. Looking at the mechanism of cure in various diseases of the gut led us to the thinking that reversal of intestinal dysbiosis could improve gut GVHD,&rdquo; the researchers wrote.In this study, fecal samples for FMT were obtained from healthy donors who passed screening for transmissible disease. All patients were given 100 gm of stool in solution, which was administered once daily for four consecutive days through a naso-jejunal tube. The patients received FMT as second-line treatment. The researchers noted that adverse events that were first noted within one week of infusion of FMT were evaluated for safety. Response to FMT was evaluated at 14 days, and complete resolution of symptoms was considered a complete response.According to the results, FMT was well tolerated by all patients. No side effects related to FMT were suspected or confirmed in any patients, the researchers noted.The researchers concluded, &ldquo;FMT can be considered as a potential, relatively safe, and well tolerated option for treatment of acute gut GVHD in [patients undergoing] alloHCT.&rdquo;Read more at: <a href="https://tct.confex.com/tct/2021/meetingapp.cgi/Paper/16885">https://tct.confex.com/tct/2021/meetingapp.cgi/Paper/16885</a>Kathrotiya M, et al. Fecal Microbiota Transplant: Is It an Effective Option for Treating Steroid Refractory Acute Graft Versus Host Disease of Gut? Published for the 2021 TCT Meetings of ASTCT &amp; CIBMTR Digital Experience; February 8-12, 2021.

Jordana Jampel

Modernization and the Rising Burden of IBD: New Insights From a Global Study

Gastroenterology

FDA Approves Novel Blood Test for Alzheimer’s Detection

Dementia

Andrew Moreno

Is Plasma Mannose-Binding Lectin a Clue to Higher VTE Risk?

Latest News

Fecal Microbiota Transplant Effective for Treating Acute GVHD

TCT 2021

Fecal microbiota transplant (FMT) is a relatively safe and viable treatment option for acute gut graft-versus-host disease (GVHD), according to a study presented at the 2021 ...

About Us

Editorial Policy

Advertising

Contact Us

eNewsletters

Contribute

Career Center

MashupMD

Blood Cancers Today

Cancer Nursing Today

GU Oncology Now

Urban Health Today

Anemia

Deep Vein Thrombosis

Essential Thrombocythemia

Hemophilia

Immune Thrombocytopenic Purpura

Myelodysplastic Syndromes

Myelofibrosis

Myeloproliferative Neoplasms

Polycythemia Vera

Pulmonary Embolism

Sickle Cell Disease

Thrombocytopenia

Thrombophilia

Thrombosis

Thrombotic Thrombocytopenic Purpura

Venous Thromboembolism

von Willebrand Disease

Heme Today

Acute Kidney Injury

ADPKD

Anemia and Kidney Disease

Chronic Kidney Disease

COVID-19 and Kidney Disease

Diabetes and Hypertension

End-Stage Renal Disease

Gout

Hyperkalemia

IgAN

Kidney Transplantation

Metabolic Acidosis

Nephrology Times

HER2 Breast Cancer

HR Breast Cancer

Triple-Negative Breast Cancer

Genetics & Breast Cancer

Breast Cancers Today

Atherosclerotic Disease

Atrial Fibrillation

Heart Failure

Hypertension

Interventional Cardiology

Lipid Management

Practice Tips With Dr. Lichaa

Preventive Cardiology

Stroke

Cardiology

Breast Cancer

Gynecologic Cancer

Head and Neck Cancer

Skin Cancer

Oncology

Sleep

Urology

Diabetes

Ophthalmology

— Demodex Blepharitis

Neurology

Rheumatology

Pulmonology

Infectious Diseases

— HIV

Health and Wellness

Lupus

Future of Medicine

Orthopedics

Pharmacology

Career News

More

Conferences

CardioNerds

The Sleep Source With Dr. Morse

Rheumatology Rounds With Dr. Maheswaranathan

Partners

Expert Interviews

Subscribe