Kaitlyn D’Onofrio

DocwireNews

A study evaluated the correlation between perceived fatigue and health-related quality of life (HRQoL), social support, and cognition in patients with multiple sclerosis (MS).The study included 128 Argentinian patients with MS. The mean age was 40&plusmn;10.49 years, 75 patients (58 percent) were female, and the mean Expanded Disability Status Scale (EDSS) was 2.43&plusmn;1.87. Patients were assessed using the Fatigue Severity Scale (FSS), EDSS, Beck&rsquo;s Depression Inventory II (BDI-II), International Quality of Life questionnaire (MusiQoL), Medical Outcomes Study Social Support Survey, Brief International Cognitive Assessment for MS, 7/24 Spatial Recall Test, Paced Auditory Serial Task (PASAT-3), and word list generation task.Just over half of patients (n=66; 51.6%) had fatigue. Patients with versus without fatigue presented significant differences in EDSS and BDI II (P&lt;0.001). Correlations were observed between fatigue and age, EDSS, and BDI II (P&lt;0.05). In terms of HRQoL, MusiQoL significantly differed between fatigued versus non-fatigued patients (P&lt;0.05). FSS independently predicted HRQoL (typified &beta;=&ndash;0.612 and &ndash;0.287; P&lt;0.05). Compared with non-fatigued patients, those with fatigue had fewer friends in their social support network (P=0.031) and poorer PASAT-3 performance, the latter of which was independently precited by FSS (&beta;=-0.280; P=0.009).&ldquo;Fatigue is one of the most common symptoms in MS and has a great impact on patients&rsquo; daily life. This study highlights the importance of studying fatigue and treating it properly, since otherwise, it contributes to the dysfunction of patients daily life with psychological and social consequences,&rdquo; the study authors concluded.

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Perceived Fatigue and its Effect on HRQoL in MS

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A study evaluated the correlation between perceived fatigue and health-related quality of life (HRQoL), social support, and cognition in patients with multiple sclerosis ...

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