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There is an&nbsp;association between rheumatoid arthritis (RA) and&nbsp;dysbiotic&nbsp;oral microbiomes. In these studies, there is also a&nbsp;presence of extensive periodontitis, an&nbsp;infection of the tissues&nbsp;in your mouth.&nbsp;In a study published in&nbsp;Arthritis &amp; Rheumatology,&nbsp;researchers&nbsp;investigated&nbsp;the role of RA in modulating the periodontal microbiome by comparing periodontally healthy individuals with RA to those without RA.&nbsp;<blockquote class="twitter-tweet" data-width="500" data-dnt="true">
Our new paper is out! <a href="https://twitter.com/hashtag/rheumatoidarthritis?src=hash&amp;ref_src=twsrc%5Etfw">#rheumatoidarthritis</a> <a href="https://twitter.com/hashtag/microbiome?src=hash&amp;ref_src=twsrc%5Etfw">#microbiome</a> <a href="https://twitter.com/hashtag/periodontitis?src=hash&amp;ref_src=twsrc%5Etfw">#periodontitis</a> <a href="https://t.co/Dsm0jpdbvk">https://t.co/Dsm0jpdbvk</a>?
&mdash; Akshay Paropkari (@akshayparopkari) <a href="https://twitter.com/akshayparopkari/status/972237878091595777?ref_src=twsrc%5Etfw">March 9, 2018</a>
</blockquote><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>In this study, participants were&nbsp;periodontally healthy individuals (22 with RA and 19 without RA). Researchers collected subgingival plaque&nbsp;from each of the participants,&nbsp;and the 16S gene was sequenced on an Illumina&nbsp;MiSeq&nbsp;platform.&nbsp;QIIME and&nbsp;PhyloToAST&nbsp;pipelines&nbsp;were used to examine bacterial biodiversity and co&#8208;occurrence patterns.&nbsp;<blockquote class="twitter-tweet" data-width="500" data-dnt="true">
Microbiota gingival y citrulina en AR&hellip; Dysbiotic Subgingival Microbial Communities in Periodontally Healthy Patients With Rheumatoid Arthritis &ndash; Lopez&#8208;Oliva &ndash; 2018 &ndash; Arthritis &amp; Rheumatology &ndash; Wiley Online Library <a href="https://t.co/meDYOCPzxP">https://t.co/meDYOCPzxP</a>
&mdash; Enrique Calvo Aranda (@enriquecalvoA) <a href="https://twitter.com/enriquecalvoA/status/1015932378504744960?ref_src=twsrc%5Etfw">July 8, 2018</a>
</blockquote><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script><blockquote class="twitter-tweet" data-width="500" data-dnt="true">
Interesting article on microbiota and arthritis: <a href="https://t.co/Zk9ESrEsGk">https://t.co/Zk9ESrEsGk</a>
&mdash; Sampurna Chakrabarti (@fluorescence_SC) <a href="https://twitter.com/fluorescence_SC/status/1013379174558552064?ref_src=twsrc%5Etfw">July 1, 2018</a>
</blockquote><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>Results showed that between patients with RA and the controls,&nbsp;subgingival microbiomes differed significantly.&nbsp;In addition, although&nbsp;Porphyromonas&nbsp;gingivalis&nbsp;and&nbsp;Aggregatibacter&nbsp;actinomycetemcomitans&nbsp;were not significantly different in each of the groups,&nbsp;Cryptobacterium&nbsp;curtum&nbsp;emerged as a robust discriminant of the microbiome in individuals with RA.&nbsp;&ldquo;Our data demonstrate that the oral microbiome in RA is enriched for&nbsp;inflammophilic&nbsp;and citrulline&#8208;producing organisms, which may play a role in the production of autoantigenic citrullinated peptides in RA,&rdquo; the researchers concluded.&nbsp;SOURCE:&nbsp;<a href="https://onlinelibrary.wiley.com/doi/abs/10.1002/art.40485">Arthritis &amp; Rheumatology&nbsp;</a>

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Extensive Periodontitis and Rheumatoid Arthritis

Rheumatology

There is an association between rheumatoid arthritis (RA) and dysbiotic oral microbiomes. In these studies, there is also a presence of extensive periodontitis, ...