Kerri Fitzgerald

DocwireNews

Vigorous exercise&nbsp;was&nbsp;associated with&nbsp;a&nbsp;lower risk of mortality in adult survivors of childhood cancer, according to a study published in&nbsp;JAMA&nbsp;Oncology&nbsp;and presented at the 2018 ASCO Annual Meeting.&nbsp;&nbsp;The multicenter cohort&nbsp;study included&nbsp;15,450 adult cancer survivors&nbsp;who were&nbsp;diagnosed before age 21&nbsp;at&nbsp;pediatric tertiary hospitals in the United States and Canada between 1970 and 1999&nbsp;who were&nbsp;enrolled in the Childhood Cancer Survivor Study, with follow-up through December 31, 2013.&nbsp;Patients self-reported vigorous exercise in metabolic equivalent task (MET)&nbsp;hours per week.&nbsp;<blockquote class="twitter-tweet" data-lang="en">
Is vigorous <a href="https://twitter.com/hashtag/exercise?src=hash&amp;ref_src=twsrc%5Etfw">#exercise</a> and change in exercise associated with a reduction in mortality in adult survivors of <a href="https://twitter.com/hashtag/childhood?src=hash&amp;ref_src=twsrc%5Etfw">#childhood</a> <a href="https://twitter.com/hashtag/cancer?src=hash&amp;ref_src=twsrc%5Etfw">#cancer</a>? Find out from <a href="https://twitter.com/sloan_kettering?ref_src=twsrc%5Etfw">@sloan_kettering</a> researchers <a href="https://t.co/esqVUUgaIQ">https://t.co/esqVUUgaIQ</a> <a href="https://twitter.com/hashtag/ASCO18?src=hash&amp;ref_src=twsrc%5Etfw">#ASCO18</a>
&mdash; JAMA Oncology (@JAMAOnc) <a href="https://twitter.com/JAMAOnc/status/1005826927511396352?ref_src=twsrc%5Etfw">June 10, 2018</a>
</blockquote><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>During a median follow-up of 9.6 years (interquartile range =&nbsp;15.5 years), 1,063 deaths&nbsp;were&nbsp;reported:&nbsp;811&nbsp;were&nbsp;health-related, 120&nbsp;were&nbsp;recurrence/progression of primary cancer,&nbsp;and&nbsp;132&nbsp;were&nbsp;external/unknown causes.&nbsp;At 15 years, the cumulative incidence of all-cause mortality was:&nbsp;<ul>
<li data-leveltext="&#61623;" data-font="Symbol" data-listid="6" aria-setsize="-1" data-aria-posinset="1" data-aria-level="1">11.7% for those who exercised 0 MET-hours per week&nbsp;</li>
<li data-leveltext="&#61623;" data-font="Symbol" data-listid="6" aria-setsize="-1" data-aria-posinset="2" data-aria-level="1">8.6% for 3-6&nbsp;MET-hours per week&nbsp;</li>
<li data-leveltext="&#61623;" data-font="Symbol" data-listid="6" aria-setsize="-1" data-aria-posinset="3" data-aria-level="1">7.4% for 9-12&nbsp;MET-hours per week&nbsp;</li>
<li data-leveltext="&#61623;" data-font="Symbol" data-listid="6" aria-setsize="-1" data-aria-posinset="3" data-aria-level="1">8.0%&nbsp;for 15-21&nbsp;MET-hours per week&nbsp;</li>
</ul><blockquote class="twitter-tweet" data-partner="tweetdeck">
Among 5,689 survivors in this group, those who increased the intensity of their exercise over an eight-year period had a 40% reduction in their mortality rate compared with those with a low level of exercise. <a href="https://twitter.com/hashtag/ChildhoodCancer?src=hash&amp;ref_src=twsrc%5Etfw">#ChildhoodCancer</a> <a href="https://twitter.com/hashtag/ASCO18?src=hash&amp;ref_src=twsrc%5Etfw">#ASCO18</a>
&mdash; Memorial Sloan Kettering Cancer Center (@sloan_kettering) <a href="https://twitter.com/sloan_kettering/status/1003276257784750080?ref_src=twsrc%5Etfw">June 3, 2018</a>
</blockquote><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script> 
Among a subset of 5,689 survivors, increased exercise over an 8-year period was associated with a 40% reduction in all-cause mortality rate compared with maintenance of low exercise (rate ratio&nbsp;=&thinsp;0.60; 95% CI 0.44-0.82;&nbsp;P=0.001).&nbsp;Source:&nbsp;<a href="https://jamanetwork.com/journals/jamaoncology/article-abstract/2683624">JAMA&nbsp;Oncology&nbsp;</a>

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Vigorous exercise was associated with a lower risk of mortality in adult survivors of childhood cancer, according to a study published in JAMA Oncology and presented at ...

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