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In a study published in&nbsp;Arthritis Research &amp; Therapy, researchers used a cohort of patients with&nbsp;nonradiographic&nbsp;axial&nbsp;spondyloarthritis&nbsp;(nr-axSpA) to define the early bone changes occurring in axial&nbsp;spondyloarthritis&nbsp;(axSpA) and to define potential factors for deterioration of bone microstructure.&nbsp;&nbsp;<blockquote class="twitter-tweet" data-width="500" data-dnt="true">
Cortical bone loss is an early feature of nonradiographic axial spondyloarthritis <a href="https://t.co/JipPSpUNeW">https://t.co/JipPSpUNeW</a> <a href="https://twitter.com/hashtag/rheum?src=hash&amp;ref_src=twsrc%5Etfw">#rheum</a> <a href="https://twitter.com/hashtag/arthritis?src=hash&amp;ref_src=twsrc%5Etfw">#arthritis</a> <a href="https://t.co/tf6QERPTUY">pic.twitter.com/tf6QERPTUY</a>
&mdash; ArthritisResTher (@ArthritisRes) <a href="https://twitter.com/ArthritisRes/status/1035480548725215233?ref_src=twsrc%5Etfw">August 31, 2018</a>
</blockquote><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>For the study, 107&nbsp;patients with&nbsp;axSpA&nbsp;and 50 healthy control subjects were used.&nbsp;All participants of the study&nbsp;(who were of&nbsp;similar age,&nbsp;sex,&nbsp;and body mass index),&nbsp;were assessed for geometric, volumetric, and microstructural parameters of bone using high-resolution peripheral quantitative computed tomography (HR-pQCT) at the radius.&nbsp;The results of the study showed that the geometric and microstructural analysis by HR-pQCT&nbsp;revealed a significantly reduced cortical area (p&thinsp;=&thinsp;0.022) and cortical thickness (p&thinsp;=&thinsp;0.006) in patients with nr-axSpA,&nbsp;compared with control subjects.&nbsp;<blockquote class="twitter-tweet" data-width="500" data-dnt="true">
<a href="https://twitter.com/hashtag/CorticalBoneLoss?src=hash&amp;ref_src=twsrc%5Etfw">#CorticalBoneLoss</a> is an early feature of nonradiographic axial <a href="https://twitter.com/hashtag/Spondyloarthritis?src=hash&amp;ref_src=twsrc%5Etfw">#Spondyloarthritis</a> <a href="https://t.co/VkglSPfUiE">https://t.co/VkglSPfUiE</a> <a href="https://twitter.com/hashtag/FOAMed?src=hash&amp;ref_src=twsrc%5Etfw">#FOAMed</a> <a href="https://twitter.com/hashtag/ECM?src=hash&amp;ref_src=twsrc%5Etfw">#ECM</a>
&mdash; ECM Fisioterapisti (@1Fisioterapisti) <a href="https://twitter.com/1Fisioterapisti/status/1036901349491965953?ref_src=twsrc%5Etfw">September 4, 2018</a>
</blockquote><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>&ldquo;Bone microstructure in patients with nr-axSpA&nbsp;is characterized primarily by deterioration of cortical bone. Cortical bone loss starts early and is evident within the first 2 years of the disease,&rdquo; the researchers concluded.&nbsp;&nbsp;Check out&nbsp;an article on&nbsp;the&nbsp;<a href="https://proddocwire.wpengine.com/docwire-pick/immune-related-adverse-events/">rheumatic&nbsp;immune-related adverse events of cancer immunotherapy</a>.&nbsp;SOURCE:&nbsp;<a href="https://arthritis-research.biomedcentral.com/articles/10.1186/s13075-018-1620-1">Arthritis Research &amp; Therapy&nbsp;</a>

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In a study published in Arthritis Research &amp; Therapy, researchers used a cohort of patients with nonradiographic axial spondyloarthritis (nr-axSpA) to define the ...