Consuming caffeine could be associated with longevity for people with chronic kidney disease (CKD), according to a study published in Nephrology Dialysis Transplantation.
The study assessed 4,863 participants with CKD using the National Health and Nutrition Examination Survey 1999–2010. Researchers measured four quartiles of caffeine: < 28.2 mg/day (Q1), 28.2-103.0 (Q2), 103.01-213.5 (Q3), and > 213.5 (Q4). Median follow-up time was 60 months, at which time 1,283 participants had died.
When measuring against the Q1 cohort, the adjusted hazard ratio (HR) for all-cause mortality was 0.74 for Q2, 0.74 for Q3, and 0.78 for Q4.
Coffee May Have Another Perk for Kidney Patients. According to new research involving nearly 5,000 people with chronic kidney disease, a hike in daily caffeine intake appeared to lower their odds of an early death. https://t.co/jaGUXear1G pic.twitter.com/4r4OjtCey0
— American Heart Oklahoma (@AHAOklahoma) September 16, 2018
Researchers also analyzed the protective effects of caffeine based on source for those who consume caffeine from coffee, tea, and soft drinks and divided these participants into three groups: no consumption, consumption below median, and consumption above median. There was no significant association between caffeine consumption from coffee or tea and all-cause mortality. When compared with the no consumption group, adjusted HRs for coffee drinkers were 0.92 for the no consumption group and 0.88 for the above median group. An inverse association was made between caffeine consumption from soft drinks and all-cause mortality. When measuring against the no consumption group, the adjusted HR for the below median group was 0.77, and for the above median group was 0.69.
"Study: Caffeine may lower risk of death from kidney disease" https://t.co/3G8spMFfuR @upi
Association study, but, well.. #TeamCoffee!
"We detected an inverse association between caffeine consumption and all-cause mortality among participants with CKD." https://t.co/lrBLZ0azJN
— Timothy Caulfield (@CaulfieldTim) September 13, 2018
Researchers concluded there may be an inverse relationship between caffeine consumption and all-cause mortality for CKD patients.
“Our study showed a protective effect of caffeine consumption among patients with chronic kidney disease,” said Miguel Bigotte Vieira, a lead study author. “The reduction in mortality was present even after considering other important factors such as age, gender, race, smoking, other diseases, and diet. These results suggest that advising patients with kidney disease to drink more caffeine may reduce their mortality. This would represent a simple, clinically beneficial, and inexpensive option, though this benefit should ideally be confirmed in a randomized clinical trial.”
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