Kerri Fitzgerald

DocwireNews

A study published in the&nbsp;European Journal of Cancer Prevention&nbsp;observed&nbsp;that&nbsp;no relevant association between the use of&nbsp;certain cardiovascular disease (CVD)-preventing&nbsp;treatments, such as&nbsp;aspirin, statins, and calcium channel blockers (CCBs),&nbsp;and the risk of bladder cancer.&nbsp;However, the&nbsp;findings&nbsp;indicated&nbsp;a&nbsp;potentially favorable role for CCBs.&nbsp;Researchers analyzed data from a multicentric,&nbsp;case-controlled&nbsp;study&nbsp;conducted&nbsp;in Italy between 2003 and 2014. The study&nbsp;compared&nbsp;690&nbsp;patients with&nbsp;bladder cancer and 665 hospital controls.&nbsp;<h2>Risk of bladder cancer and specific CVD-preventing medications</h2>The findings indicated the following odds ratios&nbsp;(ORs)&nbsp;for bladder cancer in association with:&nbsp;<ul>
<li data-leveltext="&#61623;" data-font="Symbol" data-listid="1" aria-setsize="-1" data-aria-posinset="1" data-aria-level="1">regular&nbsp;aspirin use: 1.21 (95% CI, 0.87-1.68)&nbsp;</li>
<li data-leveltext="&#61623;" data-font="Symbol" data-listid="1" aria-setsize="-1" data-aria-posinset="2" data-aria-level="1">any CCB use: 0.72 (95% CI, 0.54-0.97)&nbsp;</li>
<li data-leveltext="&#61623;" data-font="Symbol" data-listid="1" aria-setsize="-1" data-aria-posinset="3" data-aria-level="1">any statin use: 1.32 (95% CI, 0.87-1.99)&nbsp;</li>
</ul><h2>An inverse risk?</h2>There was a&nbsp;slight inverse association&nbsp;between bladder cancer&nbsp;risk&nbsp;and&nbsp;duration of CCB&nbsp;use.&nbsp;&nbsp;There was&nbsp;no consistent association found with duration of use, age at first use,&nbsp;or&nbsp;frequency for aspirin and statin use. There was also no consistent association found&nbsp;with indication of use for aspirin, such as&nbsp;an analgesic or for CVD prevention.&nbsp;There was also no significant association found for various combinations of&nbsp;these&nbsp;drugs&nbsp;(OR,&nbsp;1.23;&nbsp;95% CI,&nbsp;0.31-4.85).&nbsp;<a href="https://proddocwire.wpengine.com/abstracts/hem-onc-abstracts/hypofractionated-radiation-bladder-cancer/">Accelerated Hypofractionated Radiation Therapy for Elderly Frail Bladder Cancer Patients Unfit for Surgery or Chemotherapy</a>&nbsp;<a href="https://proddocwire.wpengine.com/abstracts/optimal-anticoagulant-therapy/">The optimal anticoagulant therapy for mechanical heart valves in a gallbladder cancer patient with hepatic metastases: A case report</a>&nbsp;Source: <a href="https://journals.lww.com/eurjcancerprev/Abstract/2019/03000/Bladder_cancer_risk_in_users_of_selected_drugs_for.3.aspx">European Journal of Cancer Prevention</a>

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A study published in the European Journal of Cancer Prevention observed that no relevant association between the use of certain cardiovascular disease ...

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