Rob Dillard

DocwireNews

<p>Adolescents and young adults who underwent surgery stand a higher risk of opioid dependency if long-term opioid use exists within their families, according to a <a href="https://jamanetwork.com/journals/jamasurgery/article-abstract/2726600">study</a> published in <em>JAMA Surgery </em>by researchers from the University of Michigan.<p>In this retrospective cohort study, researchers utilized insurance claims data generated by a commercial database from January 2010 to June 2016 to study 346,251 opioid-na&iuml;ve patients, aged 13 to 21 (mean age, 17, 50.7% female), who underwent one of 11 surgical and dental procedures such as wisdom tooth extraction, appendix removal, hernia repair, and knee and shoulder surgery, and who were listed as dependents on a family insurance plan. Data from patients enrolled with private employer-based insurance plans were also included.</p><blockquote class="twitter-tweet" data-width="500" data-dnt="true">
<p lang="en" dir="ltr">"New research shows that when a teen is prescribed an opioid painkiller after minor surgery, his or her odds for long-term abuse nearly doubles if someone living at home already has an opioid use problem." <a href="https://twitter.com/hashtag/Opioids?src=hash&amp;ref_src=twsrc%5Etfw">#Opioids</a> <a href="https://twitter.com/hashtag/Addiction?src=hash&amp;ref_src=twsrc%5Etfw">#Addiction</a>&hellip; <a href="https://t.co/roYAlsmRFY">https://t.co/roYAlsmRFY</a></p>
<p>&mdash; RyeACT Coalition (@RyeACTCoalition) <a href="https://twitter.com/RyeACTCoalition/status/1100903478065537024?ref_src=twsrc%5Etfw">February 27, 2019</a></p>
</blockquote><p><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script></p><h2><strong>Family Member Use Affects the Young</strong></h2><p>The study implemented generalized estimating equations with robust SEs clustered at family level to model persistent opioid usage as a function of ongoing opioid use among family members; controlling for procedure, total morphine milligram equivalents of the initial prescription fill, as well as patient and family characteristics. Researchers defined opioid use in family members as having at least one (family member) who either filled a 120-day supply prescription or more during the 12 months prior to the procedure date or having filled three or more opioid prescriptions in the 90 days before a procedure.</p><p>Among the total number of studied patients, 74.3% had an initial opioid fill, and of those, 4.3% had a family member experiencing long-term opioid use. Prevalent opioid use occurred in 4.1% of patients with long-term opioid use in a family member compared with only 2.4% without family members using opioids long-term (OR=1.54; 95% CI, 1.39 to 1.71).</p><blockquote class="twitter-tweet" data-width="500" data-dnt="true">
<p lang="en" dir="ltr">Family history is a risk factor for long-term opioid use  <a href="https://t.co/GKS7YDM7gp">https://t.co/GKS7YDM7gp</a> <a href="https://twitter.com/hashtag/fastattach?src=hash&amp;ref_src=twsrc%5Etfw">#fastattach</a> <a href="https://twitter.com/hashtag/nea?src=hash&amp;ref_src=twsrc%5Etfw">#nea</a> <a href="https://t.co/BmmYlnOjai">pic.twitter.com/BmmYlnOjai</a></p>
<p>&mdash; Vyne Dental (@vynedental) <a href="https://twitter.com/vynedental/status/1100952705059770369?ref_src=twsrc%5Etfw">February 28, 2019</a></p>
</blockquote><p><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script></p><h2><strong>Opioid Association Remains Unclear</strong></h2><p>The study results suggested that long-term opioid use among family members is correlated with ongoing opioid use among na&iuml;ve adolescents and young adults who underwent surgical and dental procedures. Whether the association is due to genetic predisposition, parenting behaviors, or simply the use of the opioid prescription by a member of the family, remains unclear, according to the study authors.</p><blockquote class="twitter-tweet" data-width="500" data-dnt="true">
<p lang="en" dir="ltr">Association Between Long-term Opioid Use in Family Members and Persistent Opioid Use After Surgery Among Adolescents and Young Adults. <a href="https://t.co/oNifVu5XWz">https://t.co/oNifVu5XWz</a></p>
<p>&mdash; painmanwise (@painmanwise) <a href="https://twitter.com/painmanwise/status/1101074997517434880?ref_src=twsrc%5Etfw">February 28, 2019</a></p>
</blockquote><p><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script></p><p>&ldquo;We are trying to better understand what impacts a young adult&rsquo;s risk of chronic opioid use after the first time they are prescribed an opioid,&rdquo; researchers <a href="https://www.eurekalert.org/pub_releases/2019-02/mm-u-oui022719.php">stated</a> in a press release. They suggested providers discuss with families the potential hazards commonly associated with continued opioid use while facilitating help for patients still seeking refills in the subsequent months following a procedure.</p><p>They added that physicians &ldquo;should screen young patients for long-term opioid use in their families and implement heightened efforts to prevent opioid dependence among patients with this important risk factor.&rdquo;</p><p>Source: <a href="https://jamanetwork.com/journals/jamasurgery/article-abstract/2726600">JAMA Surgery</a>, <a href="https://www.eurekalert.org/pub_releases/2019-02/mm-u-oui022719.php">EurekAlert</a></p><div class="mceTemp"></div><div class="mceTemp"></div></p>


Brandon Twyford

DESTINY-Breast09 Demonstrates First-Line Superiority of Enhertu Plus Pertuzumab in HER2-Positive Metastatic Breast Cancer

HER2 Breast Cancer

Trodelvy Plus Keytruda Significantly Improves Progression-Free Survival in PD-L1+ mTNBC, Phase III Data Show

Triple-Negative Breast Cancer

Jordana Jampel

Actress Michelle Trachtenberg's Premature Death From Diabetes Reveals Dangers of Chronic Complications

Diabetes

Latest News

Long-Term Family Opioid Use Poses a High Risk of Adolescent Opioid Dependency Following Surgery

Pharmacology

Adolescents and young adults who underwent surgery stand a higher risk of opioid dependency if long-term opioid use exists within their families, according to a study ...

About Us

Editorial Policy

Advertising

Contact Us

eNewsletters

Contribute

Career Center

MashupMD

Blood Cancers Today

Cancer Nursing Today

GU Oncology Now

Urban Health Today

Bile Duct Cancer

Colorectal Cancer

Gastroesophageal Cancer

Gastric Cancer

GEP-NETs

GIST

Liver Cancer

Pancreatic Cancer

GI Oncology Now

Anemia

Deep Vein Thrombosis

Essential Thrombocythemia

Hemophilia

Immune Thrombocytopenic Purpura

Myelodysplastic Syndromes

Myelofibrosis

Myeloproliferative Neoplasms

Polycythemia Vera

Pulmonary Embolism

Sickle Cell Disease

Thrombocytopenia

Thrombophilia

Thrombosis

Thrombotic Thrombocytopenic Purpura

Venous Thromboembolism

von Willebrand Disease

Heme Today

Acute Kidney Injury

ADPKD

Anemia and Kidney Disease

Chronic Kidney Disease

COVID-19 and Kidney Disease

Diabetes and Hypertension

End-Stage Renal Disease

Gout

Hyperkalemia

IgAN

Kidney Transplantation

Metabolic Acidosis

Nephrology Times

HR Breast Cancer

Genetics & Breast Cancer

Breast Cancers Today

Atherosclerotic Disease

Atrial Fibrillation

Heart Failure

Hypertension

Interventional Cardiology

Lipid Management

Practice Tips With Dr. Lichaa

Preventive Cardiology

Stroke

Cardiology

Breast Cancer

Gynecologic Cancer

Head and Neck Cancer

Skin Cancer

Oncology

Sleep

Urology

Ophthalmology

— Demodex Blepharitis

Neurology

Rheumatology

Gastroenterology

Pulmonology

Infectious Diseases

— HIV

Health and Wellness

Lupus

Future of Medicine

Orthopedics

Career News

More

Conferences

CardioNerds

The Sleep Source With Dr. Morse

Rheumatology Rounds With Dr. Maheswaranathan

Partners

Expert Interviews

Subscribe