DocWire News Editors

DocwireNews

<h2 class="entry-title"><a href="https://www.docwirenews.com/hematology-oncology/preliminary-examination-of-celiac-plexus-radiosurgery-for-cancer-related-pain-reduction/">Preliminary Examination of Celiac Plexus Radiosurgery for Cancer-Related Pain Reduction</a><p>According to an article, published in the&nbsp;<em>International Journal of Radiation Oncology, Biology, Physics</em>, there is a need to improve contemporary approaches in palliative care of patients with refractory epigastric or mid-back pain associated with locally advanced abdominal malignancies, especially&nbsp;<a href="https://www.cancer.gov/types/pancreatic">pancreatic cancer</a>. The researchers, led by Liat Hammer, evaluated ablative radiation therapy targeted at the celiac plexus to alleviate this pain, and reported that &ldquo;Celiac plexus radiosurgery appears to alleviate cancer-related pain.</p><h2 class="entry-title"><a href="https://www.docwirenews.com/hematology-oncology/heart-rate-variability-parameters-for-predicting-survival-in-lung-cancer-with-brain-metastases/">Heart Rate Variability Parameters for Predicting Survival in Lung Cancer With Brain Metastases</a></h2><p>In an article, published in <em>Frontiers in Neuroscience</em>, researchers sought to uncover associations between heart rate variability (HRV) and overall survival (OS) in patients with lung cancer with brain metastases (LCBM). The study&rsquo;s co-lead authors, Shuang Wu and Guangqiao Li, reported that decreased root mean square of successive differences (RMSSD)&mdash;one of the time parameters of HRV assessed in the study&mdash;was independently associated with shorter survival time in patients with LCBM.</p><h2 class="entry-title"><a href="https://www.docwirenews.com/docwire-pick/hem-onc-picks/constructing-a-planning-model-for-volumetric-modulated-arc-therapy-in-the-treatment-of-breast-cancer/">Constructing a Planning Model for Volumetric Modulated Arc Therapy in the Treatment of Breast Cancer</a></h2><p>Researchers from the Department of Medical Physics at Instituto Zunino &ndash; Fundaci&oacute;n Marie Curie in C&oacute;rdoba, Argentina, set out to construct a knowledge-based&nbsp;<a href="https://my.clevelandclinic.org/health/treatments/17626-volumetric-modulated-arc-therapy-vmat#:~:text=Volumetric%20Modulated%20Arc%20Therapy%20(VMAT)%20uses%20photons%20(W%2D,a%20complete%20three%2Ddimensional%20manner.">volumetric modulated arc therapy</a>&nbsp;(VMAT) planning model to enable the treatment of breast cancer without lymph node irradiation. Their article, published in the&nbsp;<em>Journal of Medical Physics</em>, reported that they successfully implemented two RapidPlan&trade; (RP) models for breast cancer treatment that reduced planning time and improved treatment planning efficiency while ensuring high-quality treatment plans.</p><h2 class="entry-title"><a href="https://www.docwirenews.com/docwire-pick/hem-onc-picks/biomarkers-for-targeted-inhibitors-in-cms4-kras-mutated-colorectal-cancers/">Biomarkers for Targeted Inhibitors in CMS4 KRAS-Mutated Colorectal Cancers</a></h2><p>Over half of&nbsp;<a href="https://www.docwirenews.com/hematology-oncology/rates-of-early-onset-crc-rising-in-white-adults-under-50/">colorectal cancers</a>&nbsp;(CRCs) are wired to RAS/RAF/MEK/ERK pathway oncogenic signaling; However, the activity of therapeutic inhibitors targeted at this pathway has been &ldquo;disappointing,&rdquo; according to Mingli Yang and colleagues. They investigated MEK inhibition (MEKi)-associated resistance signaling, and CRC subpopulations that may be sensitive to biomarker-informed treatment regimens. In their study, published in&nbsp;<em>BMC Cancer</em>, the team &ldquo;identified SRC as a common targetable node&mdash;an Achilles&rsquo; heel&mdash;in MEKi-targeted therapy-associated resistance in mesenchymal stem-like CRCs, which may help development of a biomarker-driven drug combination (MEKi&thinsp;+&thinsp;SRCi) to treat problematic subpopulations of CRC.&rdquo;</p></h2>


Jordana Jampel

Glycan-Targeting Novel Vaccine Shows Promise for Vast Virus Protection

Infectious Disease

Sara Nunnery, MD, MSCI

Reclassifying HER2: What Oncologists Need to Know About HER2-Low and -Ultralow Breast Cancer

HER2 Breast Cancer

Jeffrey Perl, MD

Joel M. Topf, MD, FACP

Thoughts From the 2025 Lazarus Award Winner

NKF Spring Clinical Meetings 2025

Latest News

Oncology Round-Up: Celiac Plexus Radiosurgery, Heart Rate Variability, and More

Oncology

Preliminary Examination of Celiac Plexus Radiosurgery for Cancer-Related Pain Reduction
 ...

About Us

Editorial Policy

Advertising

Contact Us

eNewsletters

Contribute

Career Center

MashupMD

Blood Cancers Today

Cancer Nursing Today

GU Oncology Now

Urban Health Today

Bile Duct Cancer

Colorectal Cancer

Gastroesophageal Cancer

Gastric Cancer

GEP-NETs

GIST

Liver Cancer

Pancreatic Cancer

GI Oncology Now

Anemia

Deep Vein Thrombosis

Essential Thrombocythemia

Hemophilia

Immune Thrombocytopenic Purpura

Myelodysplastic Syndromes

Myelofibrosis

Myeloproliferative Neoplasms

Polycythemia Vera

Pulmonary Embolism

Sickle Cell Disease

Thrombocytopenia

Thrombophilia

Thrombosis

Thrombotic Thrombocytopenic Purpura

Venous Thromboembolism

von Willebrand Disease

Heme Today

Acute Kidney Injury

ADPKD

Anemia and Kidney Disease

Chronic Kidney Disease

COVID-19 and Kidney Disease

Diabetes and Hypertension

End-Stage Renal Disease

Gout

Hyperkalemia

IgAN

Kidney Transplantation

Metabolic Acidosis

Nephrology Times

HR Breast Cancer

Triple-Negative Breast Cancer

Genetics & Breast Cancer

Breast Cancers Today

Atherosclerotic Disease

Atrial Fibrillation

Heart Failure

Hypertension

Interventional Cardiology

Lipid Management

Practice Tips With Dr. Lichaa

Preventive Cardiology

Stroke

Cardiology

Breast Cancer

Gynecologic Cancer

Head and Neck Cancer

Skin Cancer

Sleep

Urology

Diabetes

Ophthalmology

— Demodex Blepharitis

Neurology

Rheumatology

Gastroenterology

Pulmonology

Infectious Diseases

— HIV

Health and Wellness

Lupus

Future of Medicine

Orthopedics

Pharmacology

Career News

More

Conferences

CardioNerds

The Sleep Source With Dr. Morse

Rheumatology Rounds With Dr. Maheswaranathan

Partners

Expert Interviews

Subscribe