Kerri Fitzgerald

DocwireNews

The HPV FOCAL trial published in&nbsp;JAMA&nbsp;found that women who underwent&nbsp;cervical cancer screening with human papillomavirus (HPV) testing&nbsp;had&nbsp;a significantly lower incidence of cervical precancer at 48-month follow-up than&nbsp;women who underwent&nbsp;a Papanicolaou (Pap) test alone.&nbsp;&nbsp;The randomized&nbsp;study was conducted&nbsp;in an organized Cervical Cancer Screening Program in Canada, and patients&nbsp;(25-65 years) were recruited through 224 collaborating clinicians&nbsp;between January 2008 and&nbsp;May 2012.&nbsp;&nbsp;<a href="https://twitter.com/cnnhealth/status/1014192109782528002">https://twitter.com/cnnhealth/status/1014192109782528002</a>Researchers enrolled&nbsp;19,009 women&nbsp;who&nbsp;were randomized to&nbsp;receive HPV testing (n=9,552) and&nbsp;Pap testing&nbsp;via&nbsp;liquid-based cytology&nbsp;(n=9,457). Women&nbsp;who received HPV testing&nbsp;and had negative&nbsp;results returned at 48 months. Women&nbsp;who received Pap testing and had negative results&nbsp;returned at 24&nbsp;and, if negative,&nbsp;again&nbsp;48 months. At 48-months, both groups received HPV and&nbsp;Pap&nbsp;co-testing.&nbsp;<blockquote class="twitter-tweet" data-width="500" data-dnt="true">
News: Primary <a href="https://twitter.com/hashtag/HPV?src=hash&amp;ref_src=twsrc%5Etfw">#HPV</a> screening detects cervical neoplasia earlier and more accurately than cytology. Reported this week in <a href="https://twitter.com/JAMA_current?ref_src=twsrc%5Etfw">@JAMA_current</a> by Gina Ogilvie and colleagues. <a href="https://twitter.com/gina_ginao?ref_src=twsrc%5Etfw">@gina_ginao</a> <a href="https://twitter.com/hashtag/HPVFOCAL?src=hash&amp;ref_src=twsrc%5Etfw">#HPVFOCAL</a> <a href="https://twitter.com/hashtag/cervicalcancer?src=hash&amp;ref_src=twsrc%5Etfw">#cervicalcancer</a> <a href="https://twitter.com/BCCancer?ref_src=twsrc%5Etfw">@BCCancer</a> <a href="https://twitter.com/CC_ARCC?ref_src=twsrc%5Etfw">@CC_ARCC</a> <a href="https://t.co/01R0MIU33i">https://t.co/01R0MIU33i</a>
&mdash; medwireNews (@medwireNews) <a href="https://twitter.com/medwireNews/status/1014456829399764992?ref_src=twsrc%5Etfw">July 4, 2018</a>
</blockquote><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>At 48 months, significantly fewer cervical intraepithelial neoplasia&nbsp;(CIN) grade 3 or worse (CIN3+)&nbsp;and CIN&nbsp;grade&nbsp;2&nbsp;or worse&nbsp;(CIN2+)&nbsp;were detected in the&nbsp;HPV testing group. The CIN3+ incidence rate was 2.3&nbsp;per&nbsp;1,000 in the&nbsp;HPV&nbsp;group versus 5.5 per&nbsp;1,000 in the Pap group (risk ratio&nbsp;[RR] = 0.42). The CIN2+ incidence rate at&nbsp;was 5.0&nbsp;per&nbsp;1,000 versus&nbsp;10.6&nbsp;per&nbsp;1,000, respectively (RR=0.47).&nbsp;&nbsp;Source:&nbsp;<a href="https://jamanetwork.com/journals/jama/fullarticle/2686793">JAMA&nbsp;</a>

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The HPV FOCAL trial published in JAMA found that women who underwent cervical cancer screening with human papillomavirus (HPV) testing had a significantly lower incidence ...

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