Ivania Valdés Araya

DocwireNews

Ivania Vald&eacute;s Araya, a PhD student at Universidad Mayor in Chile, discusses her research on the role of the tumor microbiome in the lung adenocarcinoma immune microenvironment.&ldquo;We wanted to know which part of the bacteria present within the tumors is interacting with the host and describe the mechanisms that are involved in this relationship,&rdquo; she said.Ms. Vald&eacute;s Araya and colleagues presented an abstract titled &ldquo;Role of the tumor microbiome in the lung adenocarcinoma immune microenvironment through multi meta-omics analysis&rdquo; during the American Association for Cancer Research Annual Meeting 2024. She explained the results of the study, which were presented during a mini-symposium at the annual meeting.&ldquo;We found an increase of some potentially pathogenic bacteria within the adenocarcinoma tumors and some metabolites [that have] already been described as immunosuppressive metabolites and promote this state in the patient,&rdquo; Ms. Vald&eacute;s Araya said.She spoke about the interpretation of these results and future directions for the research.&ldquo;We think that they are very exciting results since you can take this to prove it in vitro or in vivo to check that they are promoting these states and [are] actually contributing to a worse disease outcome for the patients,&rdquo; Ms. Vald&eacute;s Araya said. &ldquo;What we want to try to do is&hellip; transcriptomics to see the gene expression of some of the proteins that we already found and the metabolites.&rdquo;

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Ivania Valdés Araya, a PhD student at Universidad Mayor in Chile, discusses her research on the role of the tumor microbiome in the lung adenocarcinoma immune microenvironment.

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