Rob Dillard

DocwireNews

Researchers conducted a case-control study to assess environmental and occupational determinants as risk factors of myelodysplastic syndromes (MDS) in a Pakistani population. The results were published in Cancer Reports.In this case-control study, researchers analyzed 600 participants, including 150 de novo MDS cases and 450 age and gender-matched controls. They collated disease characteristics, sociodemographics, and exposure to environmental and occupational determinants, assessed via a questionnaire.The results showed that individuals who were exposed to arsenic (odds ratio [OR]=31.81, confidence interval [CI] 19.0-53.0, P=0.000) or benzene (OR=1.564, CI 1.07-2.27, P=0.01) using a natural source of water (OR=3.563, CI 2.29-5.53, P=0.000), and patients who were smokers (OR=3.1, P=0.000) were more likely to have MDS. Also, unmarried people were less likely to acquire MDS than married people (OR=0.239, CI 0.15-0.36, P=0.000). The results also showed that uneducated participants were more likely to have MDS than educated participants, and powdered milk drinkers were more likely to have MDS than dairy milk drinkers.&ldquo;Our results revealed that arsenic, use of natural source of water and benzene exposure might lead to higher risk of acquiring MDS,&rdquo; the researchers concluded. &ldquo;This study would be helpful to understand the aetiology of disease in Pakistani population.&rdquo;

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Environmental and Occupational Determinants of MDS

Researchers conducted a case-control study to assess environmental and occupational determinants as risk factors of myelodysplastic syndromes (MDS) in a Pakistani population. ...

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