dd-cfDNA Test as an Indicator of Transplant Rejection

Suphamai Bunnapradist, MD, MS, is a professor of medicine at the David Geffen School of Medicine at UCLA and research director of its kidney transplant program. He co-authored a study demonstrating the usefulness of a transplant rejection assessment test (Prospera) at evaluating the risk of rejection of a transplanted kidney. The test can detect elevated donor-derived cell-free DNA (dd-cfDNA), which are DNA fragments released from injured donor allograft cells.