ASH 2020 – Focused on CLL, MCL, and WM

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Zanubrutinib Is Well Tolerated, Associated with High Clinical Activity in R/R Waldenstrom Macroglobulinemia

Treatment with zanubrutinib was well tolerated and associated with high clinical activity in patients with relapsed/refractory (R/R) Waldenstrom macroglobulinemia (WM), according to a phase...

Novel DNA Vaccine Reduces Tumor Clones, Favorably Alters Immune Microenvironment in Patients with Untreated...

A novel idiotype (scFv-CCL20) DNA vaccine was associated with favorable perturbation of the immune microenvironment in patients with untreated smoldering Waldenstrom macroglobulinemia (WM), according...
Prevalence of Vascular Risk Factors High for Hispanics/Latinos

First-Line Ibrutinib Plus Venetoclax Improves Rates of uMRD in Patients With CLL and SLL

A first-line regimen consisting of once-daily ibrutinib plus venetoclax was associated with high rates of undetectable minimal residual disease (uMRD) in peripheral blood and...
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Adding Rituximab to Ixazomib as Post-AHCT Maintenance in MCL Increases Risk of Myelosuppression

A study has found that the addition of rituximab to ixazomib, when used as maintenance therapy following autologous hematopoietic cell transplant (AHCT), is associated...

Early Initiation of Zanubrutinib in CLL Improves Response, Durable Survival

Early initiation of Bruton’s tyrosine kinase inhibitor zanubrutinib in patients with chronic lymphocytic leukemia (CLL), especially in treatment-naïve patients and those who have received...

Recent Hematology and Oncology Headlines

Overtreating Older Women with Breast Cancer May Cause More Harm than Good, Study Finds

A new study found overtreating older women (over 70) with breast cancer might be detrimental, while not improving survival or recurrence. The study was...
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Hem/Onc Roundup: Financial Burden of Cancer Survivors, Brain Tumors in Kidney Cancer Patients

This week, findings from a clinical trial of children with high-risk Hodgkin lymphoma found the anti-CD30 antibody drug brentuximab vedotin effectively reduces side effects...
Study Asks ‘What Is Nursing Work?’—And It’s A Lot

Study Asks ‘What Is Nursing Work?’—And It’s A Lot

A study asking a seemingly simple question—“what is nursing work?”—yielded a complex answer: there are multiple types of labor involved, which “may be hidden...
Cancer Surpassing Heart Disease as Leading Cause of U.S. Deaths

Incidence of Gallbladder and Biliary Tract Cancer Up From 1990 to 2017

From 1990 to 2017, the incidence of and mortality due to gallbladder and biliary tract cancer (GBTC) increased, according to a study published online...