Cardio Round-Up: Inflammatory Bowel Disease Linked to VTE, CVD, HF; and More

Transthyretin Amyloid Cardiomyopathy Linked to HFpEF

Systematic evaluation should be used to increase the diagnosis of transthyretin amyloid cardiomyopathy (ATTR-CM), which is present in a significant number of heart failure (HF) with preserved ejection fraction (HFpEF) cases, according to a study published in JAMA Cardiology. “In this cohort study based in a community-based setting, ATTR-CM was present in a substantial number of cases of HFpEF with ventricular wall thickening, particularly in older men,” the researchers concluded.

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Inflammatory Bowel Disease Linked to Increased Risk of VTE, CVD, and HF

Inflammatory bowel disease (IBD) is associated with a 2.5-fold increase of venous thromboembolism (VTE), a 1.2-fold increased risk of atherosclerotic cardiovascular disease  (ASCVD), and a 2-fold increased risk of heart failure (HF), according to a literature review study published in Therapeutic Advances in Gastroenterology. 

Study Shows How Serum Fatty Acids are Linked with Early-Onset CAD

The results of a study show a link between the profile of serum fatty acids (FAs) and early-onset coronary artery disease (EOCAD). The study appeared in Therapeutic Advances in Chronic Disease. “The study provided the serum FAs profile of EOCAD and confirmed that the decrease in serum levels of DHA, DPA, and EPA was associated with EOCAD,” the researchers concluded. “These findings might contribute to understanding the cardiovascular effects of FAs, particularly the protective effects of ω-3 polyunsaturated FAs.”

Carbohydrate Antigen-125 is an Independent Predictor of AF Recurrence Following Radiofrequency Catheter Ablation

A study shows that augmented plasma carbohydrate antigen-125 (CA-125) CA-125 levels are linked to a higher risk of atrial fibrillation (AF), and can independently predict AF recurrence following radiofrequency catheter ablation (RFCA). The findings were published in BMC Cardiovascular Disorders. “Elevated CA-125 levels determined prior to RFCA are related to a higher risk of AF recurrence and are an independent predictor of 12-month AF recurrence after RFCA,” the researchers concluded. “CA-125 is an important easily available and inexpensive biomarker for predicting AF recurrence.”