Patrick Daly

DocwireNews

According to a recent study in&nbsp;Catheterization and Cardiovascular Interventions, the actual incidence of postimplant atrial fibrillation (PIAF) after patent foramen ovale closure (PFOc) was &ldquo;far greater&rdquo; than published trials have reported, and also was significantly associated with an older age at time of the PFOc procedure.The study&rsquo;s lead author, Yamini Krishnamurthy, wrote that published studies have reported a PIAF incidence of 2% to 5.5% after PFOc. The authors suggested that those underestimations were due to only patients presenting with <a href="https://www.cdc.gov/heartdisease/atrial_fibrillation.htm">atrial fibrillation</a> being evaluated, while patients with paroxysmal or silent atrial fibrillation would have been missed.Researchers enrolled 761 patients who underwent PFOc at a single center, among which they identified 35 patients with no history of atrial fibrillation who had an implantable loop recorder (ILR) implemented during a cryptogenic stroke evaluation before undergoing PFOc. Episodes of PIAF were evaluated via patient records.<h3>PIAF After PFOc Via ILR Measurements</h3>According to the authors, the mean duration of ILR monitoring in the 35 patients was 54.6 &plusmn; 39.4 weeks after implantation. Atrial fibrillation occurred in 13 (37%) patients. As described above, patients who developed PIAF were older than those who did not (62 &plusmn; 11 vs. 52 &plusmn; 14 years; p = 0.03). Among the 13 patients who developed atrial fibrillation, 12 patients developed atrial fibrillation within the first four weeks after PFOc, with a heightened frequency around week two and at the conclusion of the 12 week follow-up period. Notably, the authors reported that &ldquo;the timing of PIAF onset and termination were consistent with a postimplant inflammatory mechanism.&rdquo;In closing, the authors noted that the higher actual rate of postimplant atrial fibrillation indicates a relatively low stroke risk in these patients, though they called for larger trials to validate their findings.Visit the <a href="https://www.docwirenews.com/atrial-fibrillation/">Atrial Fibrillation Knowledge Hub</a> for More Recent Studies

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Postimplant Atrial Fibrillation After Patent Foramen Ovale Closure

Atrial Fibrillation

According to a recent study in Catheterization and Cardiovascular Interventions, the actual incidence of postimplant atrial fibrillation (PIAF) after patent foramen ovale ...

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