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Young patients with myocardial infarction who don&rsquo;t have obstructed coronary arteries tend to be female, have&nbsp;heterogeneous&nbsp;mechanistic profiles, and had similar outcomes to those&nbsp;experiencing&nbsp;MI from&nbsp;coronary&nbsp;artery disease, new study results suggested. Study researchers,&nbsp;publishing&nbsp;the results of the Variation in Recovery: Role of Gender on&nbsp;Outcomes&nbsp;of Young AMI Patients (VIRGO) study in the&nbsp;Journal of the American Heart Association, enrolled acute MI patients at a 2:1 ratio of women to men, with key outcomes set as one- and 12-month mortality and functional SAQ and psychosocial status.&nbsp;&nbsp;<blockquote class="twitter-tweet" data-width="500" data-dnt="true">
Young patients w/ MINOCA were more likely women, had a heterogeneous mechanistic profile, and had clinical outcomes comparable to those of MI&#8208;CAD patients <a href="https://t.co/klowQy517w">https://t.co/klowQy517w</a>
&mdash; JAHA (@JAHA_AHA) <a href="https://twitter.com/JAHA_AHA/status/1012487069686484992?ref_src=twsrc%5Etfw">June 29, 2018</a>
</blockquote><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>According&nbsp;to the results, 299 (11.1%) of the patient population presented with MI with no obstructed coronary arteries. Women had a five-fold higher risk of having MI without obstructed coronary arteries than men in the study population did. Those presenting with MI and no obstructed arteries also were more&nbsp;likely&nbsp;to be without traditional cardiovascular risk factors and were more prone to hypercoagulable states than those with coronary artery disease. Women with MI who had coronary&nbsp;artery&nbsp;disease&nbsp;were&nbsp;more&nbsp;likely&nbsp;to be in menopause than those presenting without obstructed arteries and to have a history of gestational diabetes.&nbsp;&nbsp;&ldquo;Patients with MI without obstructed coronary arteries had similar outcomes,&nbsp;including&nbsp;mortality and&nbsp;psychosocial&nbsp;and functional status, to MI patients with coronary artery disease,&rdquo; the authors concluded. &ldquo;The clinical profile and management of [these] patients varied by sex and phenotype. Further work is needed to better&nbsp;characterize&nbsp;these patients based on the underlying mechanism.&rdquo;&nbsp;<blockquote class="twitter-tweet" data-width="500" data-dnt="true">
Would be interested to know how many of these &ldquo;MINOCA&rdquo; are actually <a href="https://twitter.com/hashtag/SCAD?src=hash&amp;ref_src=twsrc%5Etfw">#SCAD</a> that&rsquo;s missed? <a href="https://twitter.com/SCADalliance?ref_src=twsrc%5Etfw">@SCADalliance</a> <a href="https://t.co/qATwnFsf3a">https://t.co/qATwnFsf3a</a>
&mdash; Dorian L. Beasley MD, FACC (@cardiojaydoc02) <a href="https://twitter.com/cardiojaydoc02/status/1014135398023548929?ref_src=twsrc%5Etfw">July 3, 2018</a>
</blockquote><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script><blockquote class="twitter-tweet" data-width="500" data-dnt="true">
MINOCA: there is much more than obstructive <a href="https://twitter.com/hashtag/coronary?src=hash&amp;ref_src=twsrc%5Etfw">#coronary</a> epicardial <a href="https://twitter.com/hashtag/atherosclerosis?src=hash&amp;ref_src=twsrc%5Etfw">#atherosclerosis</a> causing ischemia including <a href="https://twitter.com/hashtag/microvascular?src=hash&amp;ref_src=twsrc%5Etfw">#microvascular</a> disease, <a href="https://twitter.com/hashtag/vasospasm?src=hash&amp;ref_src=twsrc%5Etfw">#vasospasm</a> &amp; <a href="https://twitter.com/hashtag/endothelial?src=hash&amp;ref_src=twsrc%5Etfw">#endothelial</a> dysfxn, &amp; most importantly non-obstructive <a href="https://twitter.com/hashtag/CAD?src=hash&amp;ref_src=twsrc%5Etfw">#CAD</a>.<a href="https://twitter.com/emorywomenheart?ref_src=twsrc%5Etfw">@emorywomenheart</a> <a href="https://twitter.com/hashtag/angina?src=hash&amp;ref_src=twsrc%5Etfw">#angina</a> <a href="https://twitter.com/CMichaelGibson?ref_src=twsrc%5Etfw">@CMichaelGibson</a> <a href="https://t.co/HsR3X9RLt1">https://t.co/HsR3X9RLt1</a>
&mdash; Parham Eshtehardi MD (@CardioOBDoc) <a href="https://twitter.com/CardioOBDoc/status/1014938684368572418?ref_src=twsrc%5Etfw">July 5, 2018</a>
</blockquote><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>Source: <a href="http://jaha.ahajournals.org/content/7/13/e009174?etoc=">Journal of the American Heart Association</a>&nbsp;

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Young patients with myocardial infarction who don't have obstructed coronary arteries tend to be female, have heterogeneous mechanistic profiles, and had similar outcomes to ...

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