DocWire News Editors

DocwireNews

A single 15-minute&nbsp;<a href="https://proddocwire.wpengine.com/tag/troponin/">troponin</a>&nbsp;concentration measurement using a novel point-of-care assay (Tnl-Nx) produced similar results to a lab-based high-sensitivity cardiac troponin assay for the rule-out of acute&nbsp;<a href="https://proddocwire.wpengine.com/docwire-pick/rivaroxaban-linked-improved/">myocardial infarction</a>&nbsp;(MI), new study results indicate.&nbsp;Researchers for the preliminary cohort study included 354 patients presenting to the emergency department with acute MI symptoms. The authors compared the&nbsp;TnI-Nx assay to the&nbsp;hs-cTnl&nbsp;assay using area under&nbsp;receiver&nbsp;operator characteristic curve (AUC) and sensitivity, negative predictive value, and the proportion of negative test results at thresholds with 100% sensitivity. The primary study outcome was type 1 acute MI during index presentation.&nbsp;&nbsp;<blockquote class="twitter-tweet" data-width="500" data-dnt="true">
yeah &ndash; thanks <a href="https://twitter.com/JAMACardio?ref_src=twsrc%5Etfw">@JAMACardio</a> &ndash; very pleased to see this out <a href="https://twitter.com/hashtag/troponin?src=hash&amp;ref_src=twsrc%5Etfw">#troponin</a> <a href="https://twitter.com/hashtag/pointofcare?src=hash&amp;ref_src=twsrc%5Etfw">#pointofcare</a> <a href="https://t.co/xBQcFibHqJ">https://t.co/xBQcFibHqJ</a>
&mdash; I left in protest. #ChristchurchCall (@kiwiskiNZ) <a href="https://twitter.com/kiwiskiNZ/status/1052658655017893888?ref_src=twsrc%5Etfw">October 17, 2018</a>
</blockquote><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>According to the results, there was no difference between the result of the&nbsp;Tnl-Nx assay (AUC=0.975; 95% CI, 0.958 to 0.993) and the&nbsp;hs-cTnl&nbsp;(AUC=0.970; 95% CI, 0.949 to 0.990; P=0.46). A&nbsp;TnI-Nx assay result of &lt; 11 ng/L identified 56.7%&nbsp;of patients&nbsp;as low risk, with a sensitivity of 100% and a negative predictive value of 100%. In comparison, an&nbsp;hs-cTnI&nbsp;assay result of less than 3 ng/L identified 43.5% as low risk, with a sensitivity of 100%.&nbsp;<a href="https://twitter.com/cleebennett/statuses/1052927314969939969">https://twitter.com/cleebennett/statuses/1052927314969939969</a>The researchers noted in their conclusion that use of this assay in the emergency department &ldquo;may facilitate earlier decision making and could expedite the safe discharge of a large proportion of low-risk patients.&rdquo;Source: <a href="https://jamanetwork.com/journals/jamacardiology/fullarticle/2705683">JAMA Cardiology</a>

MarkAlain Déry, DO

The Significant Danger Measles Pose for Unvaccinated Children

Infectious Disease

Andrew Moreno

Antithrombotic Care in Hemophilia: A Summary of Multi-Organizational Clinical Practice Guidance

Hemophilia

James Tumlin, MD

Joel M. Topf, MD, FACP

Proteinuria Remission With Sparsentan in FSGS

NKF Spring Clinical Meetings 2025

Latest News

A New Single-test Rule-out for Acute Myocardial Infarction?

Cardiology

A single 15-minute troponin concentration measurement using a novel point-of-care assay (Tnl-Nx) produced similar results to a lab-based high-sensitivity cardiac troponin ...

About Us

Editorial Policy

Advertising

Contact Us

eNewsletters

Contribute

Career Center

MashupMD

Blood Cancers Today

Cancer Nursing Today

GU Oncology Now

Urban Health Today

Bile Duct Cancer

Colorectal Cancer

Gastroesophageal Cancer

Gastric Cancer

GEP-NETs

GIST

Liver Cancer

Pancreatic Cancer

GI Oncology Now

Anemia

Deep Vein Thrombosis

Essential Thrombocythemia

Immune Thrombocytopenic Purpura

Myelodysplastic Syndromes

Myelofibrosis

Myeloproliferative Neoplasms

Polycythemia Vera

Pulmonary Embolism

Sickle Cell Disease

Thrombocytopenia

Thrombophilia

Thrombosis

Thrombotic Thrombocytopenic Purpura

Venous Thromboembolism

von Willebrand Disease

Heme Today

Acute Kidney Injury

ADPKD

Anemia and Kidney Disease

Chronic Kidney Disease

COVID-19 and Kidney Disease

Diabetes and Hypertension

End-Stage Renal Disease

Gout

Hyperkalemia

IgAN

Kidney Transplantation

Metabolic Acidosis

Nephrology Times

HER2 Breast Cancer

HR Breast Cancer

Triple-Negative Breast Cancer

Genetics & Breast Cancer

Breast Cancers Today

Atherosclerotic Disease

Atrial Fibrillation

Heart Failure

Hypertension

Interventional Cardiology

Lipid Management

Practice Tips With Dr. Lichaa

Preventive Cardiology

Stroke

Breast Cancer

Gynecologic Cancer

Head and Neck Cancer

Skin Cancer

Oncology

Sleep

Urology

Diabetes

Ophthalmology

— Demodex Blepharitis

Neurology

Rheumatology

Gastroenterology

Pulmonology

Infectious Diseases

— HIV

Health and Wellness

Lupus

Future of Medicine

Orthopedics

Pharmacology

Career News

More

Conferences

CardioNerds

The Sleep Source With Dr. Morse

Rheumatology Rounds With Dr. Maheswaranathan

Partners

Expert Interviews

Subscribe