Systemic Infections in Patients with Leadless Pacemakers: Incidence and Outcomes

This analysis of data from the Micra IDE clinical trial program sought to examine incidence and outcomes of serious infectious events developing during follow-ups in patients with histories of Micra leadless pacemaker implantation. The researchers looked at 720 patients with the Micra device, 16 of whom had documented serious infective events during follow-up. All events were adjudicated as “unrelated to the Micra device or procedure.” Bacteremia was documented in 13 of the events, but no cases of persistent cases of bacteremia after antibiotic cessation were seen during follow-up. “In this small series of Micra patients who developed SIEs postimplant, the occurrence of bacteremia and/or endocarditis did not appear to lead to persistent bacteremia off antibiotics; most events resolved with antibiotic treatment,” the researchers wrote in their conclusion.

El-Chami M, et al. Pacing Clin Electrophysiol. 2019;doi:10.1111/pace.13752