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Citing a lack of data in medium- and long-term outcomes for critically ill patients with COVID-19 infection who develop atrial fibrillation (AF), Michael W. Foster and colleagues retrospectively assessed patients who were admitted to an intensive care unit (ICU) with COVID-19 between March and June 2020. In their article, presented at the American College of Cardiology Annual Scientific Session &amp; Expo (ACC.22), the researchers found that onset of AF in COVID-19 was associated with increased mortality and decreased survival over 18 months.The investigators noted that the mechanisms of these associations &ldquo;remain to be elucidated in future studies,&rdquo; but they proposed that &ldquo;the association of AF with cardiac injury markers may represent an atriopathy or myo-pericardiopathy in critically ill patients with SARS-CoV2 infection.&rdquo;The retrospective cohort included 211 patients, of which 47 had confirmed AF. Patients with AF during hospitalization were compared to patients without for the 18-month period. According to the article, the cohorts were statically similar in age, sex, race, and median body mass index (BMI).The researchers reported that 28% of patients in the AF group had a prior diagnosis of heart failure (HF), compared to 12% in the non-AF group (p = 0.138). Moreover, the AF group had a higher mean troponin-T level (133.6 vs. 116 ng/L; p = 0.007) and were more likely to have an outpatient prescription for BB (p = 0.031), AAD (p = 0.0001), loop diuretic (p = 0.021), and CCB (p = 0.05). Finally, the investigators observed significantly higher mortality (60 vs.35%; p = 0.007), and significantly lower survival in the AF group over 18 months.

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Citing a lack of data in medium- and long-term outcomes for critically ill patients with COVID-19 infection who develop atrial fibrillation (AF), Michael W. Foster and ...

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