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Women and older patients are consistently&nbsp;<a href="https://proddocwire.wpengine.com/cardiology/underrepresentation-women-elderly/">underrepresented</a>&nbsp;in contemporary&nbsp;<a href="https://proddocwire.wpengine.com/cardiology/swedish-adoption-study-heart-failure-heritability/">heart failure</a>&nbsp;(HF) trials, results from a new analysis published in&nbsp;JAMA Cardiology&nbsp;suggest.&nbsp;&nbsp;Researchers for the study performed a systematic search of HF trials that enrolled more than 400 patients between 2001 and 2016 (the review ended up looking at data from 118 trials). A cumulative total of 215,508 patients were included in the&nbsp;analysis, and findings were compared with large epidemiological studies.&nbsp;<a href="https://twitter.com/ACCCVQuality/statuses/1032705301819080704">https://twitter.com/ACCCVQuality/statuses/1032705301819080704</a>According to the results, about 27% (58,873 of 215,508 participants) were women. Older patients tended to be enrolled in chronic HF with preserved ejection fraction. The data also showed a higher proportion of women in trials of HF with preserved ejection fraction vs.&nbsp; those looking at reduced ejection fraction. In addition, the distribution of racial/ethnic groups was only reported in 55% of the studies surveyed (22% of participants were not white). There was a significant increase over time in enrollment of racial/ethnic group distribution over time, going from 13% in 2001-04 to 30% in 2013-16 (P=0.01).&nbsp;&ldquo;In contemporary HF trials, older patients and women are consistently underrepresented,&rdquo; the researchers wrote in their study. &ldquo;Race/ethnicity data are reported in less than half of trials; when reported, such data show that enrollment of nonwhite patients has increased over time.&rdquo;&nbsp;<blockquote class="twitter-tweet" data-width="500" data-dnt="true">
Great analysis: In HF trials, <a href="https://twitter.com/hashtag/older?src=hash&amp;ref_src=twsrc%5Etfw">#older</a> <a href="https://twitter.com/hashtag/patients?src=hash&amp;ref_src=twsrc%5Etfw">#patients</a> and <a href="https://twitter.com/hashtag/women?src=hash&amp;ref_src=twsrc%5Etfw">#women</a> are STILL consistently underrepresented. <a href="https://twitter.com/hashtag/Race?src=hash&amp;ref_src=twsrc%5Etfw">#Race</a>/<a href="https://twitter.com/hashtag/ethnicity?src=hash&amp;ref_src=twsrc%5Etfw">#ethnicity</a> <a href="https://twitter.com/hashtag/data?src=hash&amp;ref_src=twsrc%5Etfw">#data</a> are reported in less than half of clinical <a href="https://twitter.com/hashtag/trials?src=hash&amp;ref_src=twsrc%5Etfw">#trials</a>. BIG NEED for ACTION!!! <a href="https://twitter.com/WomenHeartOrg?ref_src=twsrc%5Etfw">@WomenHeartOrg</a> <a href="https://twitter.com/MayoClinicCV?ref_src=twsrc%5Etfw">@MayoClinicCV</a> <a href="https://twitter.com/SharonneHayes?ref_src=twsrc%5Etfw">@SharonneHayes</a> <a href="https://t.co/b6TV4UVwpn">https://t.co/b6TV4UVwpn</a>
&mdash; Tanja Dudenbostel, MD, FASH, FAHA (@DrDudenbostel) <a href="https://twitter.com/DrDudenbostel/status/1032316033779093504?ref_src=twsrc%5Etfw">August 22, 2018</a>
</blockquote><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script><blockquote class="twitter-tweet" data-width="500" data-dnt="true">
How has enrollment of older patients, women, and racial/ethnic minorities in <a href="https://twitter.com/hashtag/heartfailure?src=hash&amp;ref_src=twsrc%5Etfw">#heartfailure</a> trials changed over time? Now published in <a href="https://twitter.com/JAMACardio?ref_src=twsrc%5Etfw">@JAMACardio</a> <a href="https://t.co/YpZkRjGFaF">https://t.co/YpZkRjGFaF</a><a href="https://twitter.com/Ayman__Tahhan?ref_src=twsrc%5Etfw">@Ayman__Tahhan</a> <a href="https://twitter.com/mvaduganathan?ref_src=twsrc%5Etfw">@mvaduganathan</a> <a href="https://twitter.com/gcfmd?ref_src=twsrc%5Etfw">@gcfmd</a> <a href="https://twitter.com/coconnormd?ref_src=twsrc%5Etfw">@coconnormd</a> <a href="https://twitter.com/mfiuzat?ref_src=twsrc%5Etfw">@mfiuzat</a> <a href="https://twitter.com/JavedButler1?ref_src=twsrc%5Etfw">@JavedButler1</a> <a href="https://twitter.com/DCRINews?ref_src=twsrc%5Etfw">@DCRINews</a> <a href="https://twitter.com/DukeMedSchool?ref_src=twsrc%5Etfw">@DukeMedSchool</a> <a href="https://t.co/DWZZmAyDOy">pic.twitter.com/DWZZmAyDOy</a>
&mdash; Steve Greene (@SJGreene_md) <a href="https://twitter.com/SJGreene_md/status/1032293946775543808?ref_src=twsrc%5Etfw">August 22, 2018</a>
</blockquote><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script><blockquote class="twitter-tweet" data-width="500" data-dnt="true">
Enrollment trends of older patients, women, and racial/ethnic minorities in HF trials. Now published in <a href="https://twitter.com/JAMACardio?ref_src=twsrc%5Etfw">@JAMACardio</a> <a href="https://twitter.com/mvaduganathan?ref_src=twsrc%5Etfw">@mvaduganathan</a> <a href="https://twitter.com/SJGreene_md?ref_src=twsrc%5Etfw">@SJGreene_md</a> <a href="https://twitter.com/gcfmd?ref_src=twsrc%5Etfw">@gcfmd</a> <a href="https://twitter.com/mfiuzat?ref_src=twsrc%5Etfw">@mfiuzat</a> @jesse8850 <a href="https://twitter.com/gcfmd?ref_src=twsrc%5Etfw">@gcfmd</a> <a href="https://twitter.com/coconnormd?ref_src=twsrc%5Etfw">@coconnormd</a> <a href="https://twitter.com/mfiuzat?ref_src=twsrc%5Etfw">@mfiuzat</a> <a href="https://twitter.com/JavedButler1?ref_src=twsrc%5Etfw">@JavedButler1</a> <a href="https://twitter.com/EmoryCCRI?ref_src=twsrc%5Etfw">@EmoryCCRI</a> <a href="https://twitter.com/EmoryMedicine?ref_src=twsrc%5Etfw">@EmoryMedicine</a> <a href="https://twitter.com/emoryheart?ref_src=twsrc%5Etfw">@emoryheart</a>
 <a href="https://t.co/QXgWgYbZqS">https://t.co/QXgWgYbZqS</a> <a href="https://t.co/YcSJBiPtqm">pic.twitter.com/YcSJBiPtqm</a>
&mdash; Ayman Tahhan (@Ayman__Tahhan) <a href="https://twitter.com/Ayman__Tahhan/status/1032423872631582720?ref_src=twsrc%5Etfw">August 23, 2018</a>
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Diverse populations must be represented in clinical trials to ensure that treatments are effective and safe for everyone <a href="https://t.co/rmfQ7gwom5">https://t.co/rmfQ7gwom5</a>
&mdash; Jenna Kay (@jennakaymd) <a href="https://twitter.com/jennakaymd/status/1032993208941387777?ref_src=twsrc%5Etfw">August 24, 2018</a>
</blockquote><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>Source: <a href="https://jamanetwork.com/journals/jamacardiology/article-abstract/2697773?utm_source=twitter&amp;utm_medium=social_jamacard&amp;utm_term=1735922212&amp;utm_content=followers-article_engagement-image_stock&amp;utm_campaign=article_alert&amp;linkId=55912347">JAMA Cardiology</a>&nbsp;

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Women and older patients are consistently underrepresented in contemporary heart failure (HF) trials, results from a new analysis published in JAMA ...

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