CheckMate 8HW: Nivolumab Plus Ipilimumab Versus Chemotherapy for Metastatic Colorectal Cancer

By Thierry André, MD - Last Updated: March 19, 2025

Dr. Thierry André from Hôpital Saint-Antoine gives an overview of the CheckMate 8HW study that compared nivolumab plus ipilimumab against chemotherapy for patients with microsatellite instability–high or mismatch repair deficient metastatic colorectal cancer. The combination showed significant improvement in progression-free survival in patients in the first line setting.

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