Oncology Round-Up: CIN 3 Linked to Pregnancy Complications; and More

Adverse pregnancy outcomes in patients with CIN 3; electronic cigarettes are associated with high rates of relapse to cigarette use; and more oncology and hematology news featured this week on DocWire…

This Week: CIN 3 and Pregnancy Complications; Screening Model for Black Women; and More

Each week on DocWire News, editors bring you the latest in oncology and hematology news and research. In case you missed it, here are this week’s top headlines:

Keep reading for the breakdown on these top stories.

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Cervical Intraepithelial Neoplasia and Pregnancy Outcomes

Women with cervical intraepithelial neoplasia grade 3 (CIN 3) have adverse pregnancy outcomes, although the risks have attenuated over time, according to a study. The researchers found that women previously diagnosed with CIN 3 were more likely than the matched general population to have a preterm birth, especially extremely preterm birth (22 to 28 weeks: odds ratio, 3.00), or to have spontaneous preterm birth (odds ratio, 2.12); infection-related outcomes, including chorioamnionitis and infant sepsis (odds ratios, 3.23 and 1.72, respectively); or early neonatal death (odds ratio, 1.83). Results were largely similar for sibling comparison analyses. The risk differences for all outcomes were attenuated over time and disappeared for early neonatal death.

“These results suggest that women treated for CIN 3 should be recognized as ‘high-risk’ and managed accordingly to reduce the risk for adverse pregnancy outcomes,” the authors write.

Adverse Pregnancy Outcomes Reported for Women Diagnosed With CIN 3

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Breast Cancer Screening for Black Women

For Black women in the United States, initiating biennial screening at age 40 years could reduce Black-White disparities in breast cancer mortality, according to a study published online in the Annals of Internal Medicine. Screening strategies until age 74 years with varying ages of initiation and intervals were examined in a 1980 U.S. birth cohort of Black and White women.

For Black women, biennial screening from ages 45 to 74 years was most efficient, whereas biennial screening from ages 40 to 74 years was most equitable, with benefit-harm ratios closest to benchmark values for screening White women biennially from ages 50 to 74 years. In Black versus White women, initiating screening 10 years earlier reduced Black-White mortality disparities by 57 percent; life-years gained per mammogram were similar for both populations. The less effective treatment was for Black women, the more intensively they could be screened before benefit-harm ratios fell short of those experienced by White women.

Model Suggests Earlier Breast Cancer Screenings for U.S. Black Women

Read more about racial disparities in oncology on Urban Health Today:

Skin Cancer Risk Awareness and Behavior

Knowledge of skin cancer risk may influence risky behaviors, including the use of tanning beds, according to a study published in Dermatologic Surgery. In a survey, respondents with high risk scores were more likely to correctly perceive their higher risk for skin cancer. Among participants with high risk scores and those who previously used tanning beds, most reported a low likelihood of future indoor tanning.

Knowledge of High Skin Cancer Risk Might Modify Risky Behaviors

Read more about melanoma and squamous cell carcinoma on DocWire:

Utility of E-Cigarettes for Quitting Smoking

Electronic cigarettes are not as helpful as other smoking cessation aids in helping smokers successfully quit, according to a study. The researchers found that 12.6 percent of recent quit attempters used e-cigarettes to help with their quit attempt, a decline from previous years. For e-cigarette users, cigarette abstinence (9.9 percent) was lower than for no product use (18.6 percent). While not statistically significant, individuals who switched to e-cigarettes had a higher relapse rate than those who did not switch to e-cigarettes or other tobacco.

E-Cigarettes to Quit Smoking May Not Result in Success

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