Race/Ethnicity Plus Neighborhood Socioeconomic Status Affect Myeloma Survival

A study evaluated how the combination of race/ethnicity plus neighborhood socioeconomic status (SES) impacts long-term survival in patients with multiple myeloma (MM).

The researchers collected information from the 2000-2015 NCI Surveillance, Epidemiology, and End Results Program (SEER-18). SES was assessed as low, medium, and high tertiles. They estimated sub-hazard ratios (SHRs) and 95% confidence intervals (CIs) for each tertile, while adjusting for age and sex at diagnosis, stratifying data by race/ethnicity.

There was a general correlation between residing in a low SES neighborhood and poorer MM survival, but this did differ by race/ethnicity. Compared to living in a high SES neighborhood, the risk of MM-specific mortality increased by 35% (95% CI, 1.16–1.57) among Asian/Pacific Islander cases, 17% (95% CI, 1.12–1.22) among White cases, 14% (95% CI, 1.04–1.23) among Black cases, and 7% (95% CI, 0.96–1.19) among Hispanic cases.

“These results suggest that the influence of both SES and race/ethnicity should be considered when considering interventions to remedy disparities in MM survival,” the study authors wrote in their conclusion.

The results of the study were published in Cancer Causes & Control.