Continuous positive airway pressure (CPAP) treatment may not benefit very elderly individuals with obstructive sleep apnea (OSA), according to a study published in the January issue of Sleep Medicine.
Miguel Angel Martinez-Garcia, Ph.D., M.D., from the Hospital Universitario y Politecnico La Fe in Valencia, Spain, and colleagues assessed the effect of CPAP on a clinical cohort of 97 elderly patients (aged 80 years or older) with OSA. Individuals were randomly assigned to CPAP (47 patients) or not (50 patients).
The researchers found that the average use of CPAP was 4.3 hours/night (53 percent with good adherence). There were significant improvements among patients in the CPAP group for snoring, witnessed apneas, and the apnea-hypopnea index (from 41.9 to 4.9 events/hour). There were no clinical improvements in the Epworth Sleepiness scale, any domain of the Quebec Sleep Questionnaire, any neurocognitive test, OSA-related symptoms, depression/anxiety, or blood pressure levels.
“Our findings suggest that CPAP treatment is not as effective in patients over 80 years of age with OSA when compared to younger patients,” a coauthor said in a statement. “Considering the growing population of elderly patients that is being referred for sleep consultation, large clinical trials are urgently needed to try to solve key questions related to the use of CPAP in patients over the age of 75 or 80.”
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