Black Race Linked to Increased MACE Risk After PCI

MONDAY, July 6, 2020 (HealthDay News) — For patients undergoing percutaneous coronary intervention, black race is associated with an increased risk for major adverse cardiac events (MACE), according to research published online July 6 in JACC: Cardiovascular Interventions.

Mordechai Golomb, M.D., from the Cardiovascular Research Foundation in New York City, and colleagues examined race-based outcomes after percutaneous coronary intervention using data from 10 randomized trials. The correlation between race and outcomes was assessed while controlling for differences in 12 baseline covariates.

The researchers found that 90.9 percent of the 22,638 patients were white, and 4.1, 1.8, and 2.1 percent were black, Asian, and Hispanic, respectively. Among the groups, baseline and angiographic characteristics were different. The rate of five-year MACE was 18.8 percent in white patients compared with 23.9, 11.2, and 21.5 percent in black, Asian, and Hispanic patients, respectively. An independent association was seen between black race and five-year risk for MACE in a multivariate analysis (hazard ratio, 1.28).

“Rather than merely observe these differences over and over again for the next 30 years, there is an urgent need for action to address these, both locally and nationally,” write the authors of an accompanying editorial.

Several authors disclosed financial ties to the pharmaceutical industry.

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