Radiomics for Gleason Score Detection through Deep Learning

Sensors (Basel). 2020 Sep 21;20(18):E5411. doi: 10.3390/s20185411.


Prostate cancer is classified into different stages, each stage is related to a different Gleason score. The labeling of a diagnosed prostate cancer is a task usually performed by radiologists. In this paper we propose a deep architecture, based on several convolutional layers, aimed to automatically assign the Gleason score to Magnetic Resonance Imaging (MRI) under analysis. We exploit a set of 71 radiomic features belonging to five categories: First Order, Shape, Gray Level Co-occurrence Matrix, Gray Level Run Length Matrix and Gray Level Size Zone Matrix. The radiomic features are gathered directly from segmented MRIs using two free-available dataset for research purpose obtained from different institutions. The results, obtained in terms of accuracy, are promising: they are ranging between 0.96 and 0.98 for Gleason score prediction.

PMID:32967291 | DOI:10.3390/s20185411