Rheum Roundup: Drug Comparisons, Coffee and Tea and RA Risk, Tofacitinib Effects in Arthritis, and More

Osteoporosis patients have the same risk for hip and overall fractures whether they take denosumab (PROLIA from Amgen) or alendronate. Three years of follow-up in 92,355 patients found that cumulative hip fracture incidence was 3.7% in the denosumab group and 3.1% in the alendronate cohort, and cumulative incidence for any fracture was 9.0% in both groups.

Enjoy that cup of jo: Results from a long-term study found that daily coffee consumption did not increase the risk of incident rheumatoid arthritis (RA) in women, but drinking non-herbal tea was associated with a small increased RA risk.

Two case reports found that the benefits of tofacitinib may be twofold, not only treating RA but also showing a beneficial effect on periodontitis.

Belimumab has received approval from the Food and Drug Administration (FDA) to treat pediatric systemic lupus erythematosus (SLE) patients. The intravenous infusion treatment, sold under the brand name Benlysta from manufacturer GlaxoSmithKline (GSK), is the first FDA-approved treatment for pediatric SLE.

In a recent survey of SLE patients, all respondents said they would change their diet if it would help their disease, and more than four-fifths said they would be willing to take part in a clinical trial focused on diet and disease.

Researchers recently evaluated the evolution of the all-cause, cause-specific and age-specific standardized mortality ratios (SMRs) in lupus patients in Canada and found that all-cause and cause-specific SMRs have decreased over time.

Two weeks of antibiotic treatment may not be inferior to a four-week course of therapy in patients who underwent surgical drainage for native joint bacterial arthritis.

A recent study evaluated how likely patients are to partake in certain preventative RA strategies and found treatment preferences weighed significantly on how treatment is taken (oral vs. infusion), increasing reduction in risk of RA, health care professional preference, and avoiding serious side effects.

Patient-specific implants in total knee arthroplasty may lead to improved outcomes in terms of function and satisfaction.