Healthcare Unfiltered: ESMO-GI Update: The Amazing Chalabi Plot

In this episode of Healthcare Unfiltered, Dr. Chadi Nabhan spoke with Dr. Myriam Chalabi, a GI oncologist at the Netherlands Cancer Institute, who joined the show after making waves at the latest ESMO Congress for her NICHE-2 study – an assessment of neoadjuvant immune checkpoint inhibition in locally advanced dMMR colon cancer. Dr. Chalabi shared her initial inspiration behind giving neoadjuvant immunotherapy for dMMR tumors, the surprisingly positive early results that led to expanding the study, her feelings and expectations leading up to her talk at ESMO, as well as her reaction to the Twitter phenomenon with the “Chalabi Plot” – how the medical community was in awe of her rare and exceptional waterfall plot. As noted by Dr. Nabhan, this episode is a good reminder of the value in executing a well-designed clinical trial and the benefits that patients stand to gain from good science.

About Healthcare Unfiltered

Healthcare Unfiltered is an honest, raw, timely podcast tackling any and all topics in healthcare that affect stakeholders. Dr. Chadi Nabhan uses his dynamic conversational skills to challenge his guests to address controversial and important topics. He also brings on world renowned experts to discuss clinical advances in medicine.

About Chadi Nabhan, MD, MBA, FACP

Dr. Nabhan is a Hematologist and Medical Oncologist with special interests in malignant hematology as well as GU malignancies. He did two years of basic science research at Massachusetts General Hospital/Harvard Medical School before completing his residency at Loyola University in Chicago and a fellowship at Northwestern University and Robert H. Lurie Comprehensive Cancer Center. He holds an MBA in Health Care Management from Loyola University Quinlan School of Business.

Dr. Nabhan has broad experience in all healthcare settings having worked at major academic centers, large community hospitals, and industry from Fortune 14 company to start ups holding progressive leadership positions at the C suite level. Academically, Chadi has been the primary investigator on many clinical trials (investigator-initiated, cooperative groups, and pharma-sponsored), has over 300 peer-reviewed original articles, abstracts or book chapters, and serves on the editorial board of JAMA-Oncology.

Dr. Nabhan maintains active medical licenses to practice in the states of IL, IN, WI, FL, and CA. He is the creator and host of several podcasts including his own “Healthcare Unfiltered,” and the “Caris Molecular Minute Podcast.” Dr. Nabhan is board certified in Internal Medicine, Hematology, and Medical Oncology, and is a sought after speaker, moderator, and facilitator. Check out his website at www.chadinabhan.com