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JACC Basic Transl Sci. 2021 Feb 22;6(2):174-188. doi: 10.1016/j.jacbts.2020.08.012. eCollection 2021 Feb.
Exercise therapy and lower extremity revascularization both improve walking performance in symptomatic patients with peripheral artery disease. The combination of therapies provides greater benefit than either alone and may reduce the need for subsequent revascularization procedures, but further trials with longer follow-up are needed for the outcome of subsequent revascularization.